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Proteostasis Deficiencies Summary

Description: Disorders caused by imbalances in the protein homeostasis network - synthesis, folding, and transport of proteins; post-translational modifications; and degradation or clearance of misfolded proteins.

Also Known As: Protein Folding Diseases; Protein Folding Disorders; Protein Misfolding Diseases; Proteostasis Dysfunctions; Deficiencies, Proteostasis Show All >>

Networked: 234 relevant articles (9 outcomes, 8 trials/studies) for this Disease

Key Drugs and Agents for Proteostasis Deficiencies

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Proteins (Proteins, Gene) : 6 outcomes 3 studies in 78 results : IBA
  2. Molecular Chaperones (Chaperone, Molecular) : 3 outcomes in 15 results : IBA
  3. Antibodies : 1 outcome in 5 results : IBA
  4. Trehalose : 1 outcome in 2 results : IBA
  5. Biological Markers (Surrogate Marker) : 1 outcome in 1 result : IBA
  6. Carbamazepine (Tegretol) : 1 outcome in 1 result : FDA 24 Generic
  7. Allergens : 1 outcome in 1 result : IBA
  8. Amyloid (Amyloid Fibrils) : 2 studies in 69 results : IBA
  9. Enzymes : 1 study in 2 results : IBA
  10. Perforin : 1 study in 1 result : IBA
Show All >>

Diseases Related to Proteostasis Deficiencies

  1. Neurodegenerative Diseases (Neurodegenerative Disease)
  2. Alzheimer Disease (Alzheimer's Disease)
  3. Neoplasms (Cancer)
  4. Macular Degeneration (Age-Related Maculopathy)
  5. Eye Diseases (Eye Disease)
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Key Therapies for Proteostasis Deficiencies

Efficacy Chart >>
  1. Therapeutics : 1 outcome 1 study in 8 results
  2. Immunotherapy : 1 outcome in 1 result
  3. Topical Administration : 1 outcome in 1 result
  4. Chinese Traditional Medicine (Traditional Chinese Medicine) : 1 result
  5. Drug Therapy (Chemotherapy) : 1 result

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