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Liddle Syndrome Summary

Description: Familial pseudoaldosteronism characterized by autosomal dominant inheritance of hypertension with HYPOKALEMIA; ALKALOSIS; RENIN and ALDOSTERONE level decreases. It is caused by mutations in EPITHELIAL SODIUM CHANNEL beta and gamma subunits. Different mutations in the same EPITHELIAL SODIUM CHANNEL subunits can cause PSEUDOHYPOALDOSTERONISM, TYPE I, AUTOSOMAL DOMINANT.

Also Known As: Syndrome, Liddle; Pseudoaldosteronism

Networked: 106 relevant articles (1 outcomes, 5 trials/studies) for this Disease

Key Drugs and Agents for Liddle Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Mineralocorticoids : 1 outcome 2 studies in 3 results : IBA
  2. Epithelial Sodium Channel : 2 studies in 24 results : IBA
  3. Glycyrrhizic Acid (Glycyrrhizin) : 2 studies in 21 results : IBA
  4. Hydrocortisone (Cortisol) : 1 study in 7 results : FDA 176 Generic
  5. glycyrrhetyl 3-monoglucuronide : 1 study in 4 results : IBA
  6. Cortisone : 1 study in 3 results : IBA
  7. Choline (Choline Chloride) : 1 study in 1 result : IBA
  8. CDAA (Randox) : 1 study in 1 result : IBA
  9. Sodium : 15 results : IBA
  10. Apparent mineralocorticoid excess : 13 results : IBA
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Diseases Related to Liddle Syndrome

  1. Hypertension (High Blood Pressure)
  2. Gitelman Syndrome
  3. Rare Diseases (Rare Disease)
  4. Hyperaldosteronism (Conn Syndrome)
  5. Pseudohypoaldosteronism
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Key Therapies for Liddle Syndrome

Efficacy Chart >>
  1. Kampo Medicine (Kampo) : 2 results
  2. Chinese Traditional Medicine (Traditional Chinese Medicine) : 1 result

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