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Endosomal Sorting Complexes Required for Transport Summary

Description: A set of protein subcomplexes involved in PROTEIN SORTING of UBIQUITINATED PROTEINS into intraluminal vesicles of MULTIVESICULAR BODIES and in membrane scission during formation of intraluminal vesicles, during the final step of CYTOKINESIS, and during the budding of enveloped viruses. The ESCRT machinery is comprised of the protein products of Class E vacuolar protein sorting genes.

Also Known As: ESCRT Complexes; ESCRT I; ESCRT II; ESCRT III; ESCRT Machinery Show All >>

Networked: 51 relevant articles (2 outcomes, 4 trials/studies) for this Bio-Agent

Key Diseases for which Endosomal Sorting Complexes Required for Transport is Relevant

  1. Neoplasms (Cancer) : 2 outcomes 1 study in 13 results
  2. Neurodegenerative Diseases (Neurodegenerative Disease) : 1 outcome in 7 results
  3. Bacterial Infections (Bacterial Infection) : 1 outcome in 1 result
  4. Infection : 3 studies in 8 results
  5. Frontotemporal Dementia : 10 results
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Drugs Related to Endosomal Sorting Complexes Required for Transport

  1. Endosomal Sorting Complexes Required for Transport
  2. Viral RNA
  3. Tsg101 protein
  4. Proteins (Proteins, Gene)
  5. Interferons
  6. Ubiquitinated Proteins
  7. Receptor-Interacting Protein Serine-Threonine Kinases
  8. Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins
  9. N-Ethylmaleimide-Sensitive Proteins (N-Ethylmaleimide-Sensitive Fusion Protein)
  10. Ubiquitin
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Therapies Related to Endosomal Sorting Complexes Required for Transport


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