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Carney Complex Summary

Description: Autosomal dominant syndrome characterized by cardiac and cutaneous MYXOMAS; LENTIGINOSIS (spotty pigmentation of the skin), and endocrinopathy and its associated endocrine tumors. The cardiac myxomas may lead to SUDDEN CARDIAC DEATH and other complications in Carney complex patients. The gene coding for the PRKAR1A protein is one of the causative genetic loci (type 1). A second locus is at chromosome 2p16 (type 2).

Also Known As: Carney Complex, Type 1; Carney Complex, Type I; Carney Myxoma Endocrine Complex; Complex, Carney; Complex, Carney Myxoma-Endocrine Show All >>

Networked: 141 relevant articles (0 outcomes, 8 trials/studies) for this Disease

Key Drugs and Agents for Carney Complex

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase) : 4 studies in 59 results : IBA
  2. Growth Hormone (Somatotropin) : 1 study in 8 results : IBA
  3. aryl hydrocarbon receptor-interacting protein : 1 study in 5 results : IBA
  4. Hydrocortisone (Cortisol) : 1 study in 4 results : FDA 176 Generic
  5. Succinate Dehydrogenase (Fumarate Reductase) : 1 study in 2 results : IBA
  6. Prolactin : 1 study in 2 results : IBA
  7. Hecht syndrome : 1 study in 2 results : IBA
  8. Myosins (Myosin) : 1 study in 1 result : IBA
  9. Adrenocorticotropic Hormone (ACTH) : 10 results : FDA 7
  10. Pendred syndrome : 5 results : IBA
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Diseases Related to Carney Complex

  1. Acromegaly
  2. Pituitary Neoplasms (Pituitary Adenoma)
  3. Gigantism
  4. Multiple Endocrine Neoplasia (Multiple Endocrine Adenomatosis)
  5. Neurilemmoma (Schwannoma)
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Key Therapies for Carney Complex

Efficacy Chart >>
  1. Adrenalectomy : 4 results
  2. Thoracotomy : 2 results
  3. Epidural Analgesia : 1 result
  4. Chinese Traditional Medicine (Traditional Chinese Medicine) : 1 result
  5. Lasers (Laser) : 1 result

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