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AMP-Activated Protein Kinases Summary

Description: Intracellular signaling protein kinases that play a signaling role in the regulation of cellular energy metabolism. Their activity largely depends upon the concentration of cellular AMP which is increased under conditions of low energy or metabolic stress. AMP-activated protein kinases modify enzymes involved in LIPID METABOLISM, which in turn provide substrates needed to convert AMP into ATP.

Also Known As: 5'-AMP-Activated Protein Kinase; AMP-Activated Kinase; AMP-Activated Protein Kinase; AMP-Activated Protein Kinase alpha Subunit; AMP-Activated Protein Kinase alpha Subunits Show All >>

Networked: 1076 relevant articles (30 outcomes, 100 trials/studies) for this Bio-Agent

Key Diseases for which AMP-Activated Protein Kinases is Relevant

  1. Insulin Resistance : 6 outcomes 3 studies in 75 results
  2. Hyperglycemia : 3 outcomes 1 study in 17 results
  3. Reperfusion Injury : 3 outcomes 1 study in 16 results
  4. Obesity : 2 outcomes 5 studies in 80 results
  5. Fibrosis (Cirrhosis) : 2 outcomes in 10 results
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Drugs Related to AMP-Activated Protein Kinases

  1. Insulin (Novolin)
  2. Adiponectin
  3. Metformin (Glucophage)
  4. Glucose (Dextrose)
  5. AICA ribonucleotide (CAIR)
  6. Adenosine Monophosphate (AMP)
  7. Messenger RNA (mRNA)
  8. Berberine
  9. Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)
  10. Nitric Oxide (Nitrogen Monoxide)
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Therapies Related to AMP-Activated Protein Kinases

  1. Oral Administration
  2. Heterologous Transplantation (Xenotransplantation)
  3. Adjuvant Chemotherapy
  4. Caloric Restriction
  5. Bariatric Surgery
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