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Peroxiredoxins Summary

Description: A family of ubiquitously-expressed peroxidases that play a role in the reduction of a broad spectrum of PEROXIDES like HYDROGEN PEROXIDE; LIPID PEROXIDES and peroxinitrite. They are found in a wide range of organisms, such as BACTERIA; PLANTS; and MAMMALS. The enzyme requires the presence of a thiol-containing intermediate such as THIOREDOXIN as a reducing cofactor.

Also Known As: Alkyl Hydroperoxide Reductase; Alkyl Hydroperoxide Reductase C; Alkyl Hydroperoxide Reductase D; Alkylhydroperoxide Reductase; Mitochondrial Thioredoxin-Dependent Antioxidant Protein SP-22 Show All >>

Networked: 495 relevant articles (7 outcomes, 42 trials/studies) for this Bio-Agent

Key Diseases for which Peroxiredoxins is Relevant

  1. Neoplasms (Cancer) : 2 outcomes 7 studies in 94 results
  2. Shock : 1 outcome 2 studies in 24 results
  3. Filarial Elephantiasis (Lymphatic Filariasis) : 1 outcome 2 studies in 3 results
  4. Inflammation : 1 outcome 1 study in 22 results
  5. Carcinoma (Carcinomatosis) : 1 outcome 1 study in 15 results
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Drugs Related to Peroxiredoxins

  1. Reactive Oxygen Species (Oxygen Radicals)
  2. Antigens
  3. Ubiquitin
  4. Recombinant Proteins
  5. Peroxidase (Myeloperoxidase)
  6. Antibodies
  7. Nitric Oxide Synthase (NO Synthase)
  8. Interleukin-8 (Interleukin 8)
  9. Pulmonary Surfactants (Pulmonary Surfactant)
  10. Phosphoserine
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Therapies Related to Peroxiredoxins

  1. Homologous Transplantation (Allograft)
  2. Radiotherapy
  3. Drug Therapy (Chemotherapy)
  4. Heterologous Transplantation (Xenotransplantation)
  5. Caloric Restriction
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