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Neonatal Alloimmune Thrombocytopenia Summary

Description: A condition in newborns caused by immunity of the mother to PLATELET ALLOANTIGENS on the fetal platelets. The PLATELETS, coated with maternal ANTIBODIES, are destroyed and removed by the fetal MONONUCLEAR PHAGOCYTE SYSTEM. Affected infants may have INTRACRANIAL HEMORRHAGES.

Also Known As: Thrombocytopenia, Neonatal Alloimmune; Alloimmune Thrombocytopenia, Neonatal; Alloimmune Thrombocytopenias, Neonatal; Neonatal Alloimmune Thrombocytopenias; Neonatal Thrombocytopenias Show All >>

Networked: 445 relevant articles (15 outcomes, 24 trials/studies) for this Disease

Key Drugs and Agents for Neonatal Alloimmune Thrombocytopenia

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Antibodies : 3 outcomes 6 studies in 115 results : IBA
  2. Immunoglobulins (Immunoglobulin) : 3 outcomes 4 studies in 28 results : IBA
  3. Inosine Triphosphate (ITP) : 3 outcomes 1 study in 26 results : IBA
  4. Intravenous Immunoglobulins (IVIG) : 2 outcomes 3 studies in 20 results : FDA 1
  5. human 1a alloantigen (HPA-1a) : 1 outcome 2 studies in 35 results : IBA
  6. Immunoglobulin G (IgG) : 1 outcome 1 study in 22 results : IBA
  7. gamma-Globulins (gamma-Globulin) : 1 outcome in 4 results : IBA
  8. Prednisolone (Predate) : 1 outcome in 3 results : FDA 55 Generic
  9. DNA (Deoxyribonucleic Acid) : 1 outcome in 3 results : IBA
  10. Prednisone (Sone) : 1 outcome in 2 results : FDA 119 Generic
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Diseases Related to Neonatal Alloimmune Thrombocytopenia

  1. Thrombocytopenia (Thrombopenia)
  2. Intracranial Hemorrhages (Intracranial Hemorrhage)
  3. Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
  4. Hemorrhage
  5. Thrombasthenia (Glanzmann Thrombasthenia)
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Key Therapies for Neonatal Alloimmune Thrombocytopenia

Efficacy Chart >>
  1. Platelet Transfusion (Blood Platelet Transfusions) : 2 outcomes 7 studies in 67 results
  2. Splenectomy : 6 results
  3. Transplantation (Transplant Recipients) : 4 results
  4. Immunotherapy : 2 results
  5. Cesarean Section (Caesarean Section) : 2 results
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