Search Login Register

Presenilins Summary

Description: Integral membrane proteins and essential components of the gamma-secretase complex that catalyzes the cleavage of membrane proteins such as NOTCH RECEPTORS and AMYLOID BETA-PEPTIDES precursors. Mutations of presenilins lead to presenile ALZHEIMER DISEASE with onset before age 65 years.

Also Known As: Presenilin

Networked: 681 relevant articles (2 outcomes, 37 trials/studies) for this Bio-Agent

Key Diseases for which Presenilins is Relevant

  1. Alzheimer Disease (Alzheimer's Disease) : 2 outcomes 25 studies in 578 results
  2. Neuroblastoma : 2 studies in 11 results
  3. Ischemia : 2 studies in 3 results
  4. Neurodegenerative Diseases (Neurodegenerative Disease) : 1 study in 14 results
  5. Inflammation : 1 study in 12 results
Show All >>

Drugs Related to Presenilins

  1. Amyloid Precursor Protein Secretases (beta-Secretase)
  2. Amyloid (Amyloid Fibrils)
  3. Proteins (Proteins, Gene)
  4. Flavin-Adenine Dinucleotide (FAD)
  5. Presenilin-1
  6. Amyloid beta-Protein Precursor (Amyloid Protein Precursor)
  7. Amyloid beta-Peptides
  8. Calcium
  9. Apolipoproteins
  10. Apolipoproteins E (ApoE)
Show All >>

Therapies Related to Presenilins

  1. Transplantation (Transplant Recipients)
  2. Heart Transplantation (Grafting, Heart)

CureHunter Inc. provides medical information and specifically does NOT provide medical advice.
© Copyright 2003-2016 CureHunter Inc., MeSH copyright NLM, Journal Articles copyright original owners.