Search Login Register

Apolipoprotein E2 Summary

Description: One of three major isoforms of apolipoprotein E. In humans, Apo E2 differs from APOLIPOPROTEIN E3 at one residue 158 where arginine is replaced by cysteine (R158--C). In contrast to Apo E3, Apo E2 displays extremely low binding affinity for LDL receptors (RECEPTORS, LDL) which mediate the internalization and catabolism of lipoprotein particles in liver cells. ApoE2 allelic homozygosity is associated with HYPERLIPOPROTEINEMIA TYPE III.

Also Known As: APOE-epsilon 2; APOE-epsilon2; Apo E-2; Apo E2; ApoE2 Show All >>

Networked: 347 relevant articles (18 outcomes, 36 trials/studies) for this Bio-Agent

Key Diseases for which Apolipoprotein E2 is Relevant

  1. Hyperlipoproteinemias : 5 outcomes 5 studies in 62 results
  2. Alzheimer Disease (Alzheimer's Disease) : 3 outcomes 5 studies in 63 results
  3. Atherosclerosis : 2 outcomes 1 study in 18 results
  4. Hyperlipidemias (Hyperlipidemia) : 1 outcome 3 studies in 34 results
  5. Dementia (Dementias) : 1 outcome 2 studies in 14 results
Show All >>

Drugs Related to Apolipoprotein E2

  1. Apolipoproteins
  2. Apolipoproteins E (ApoE)
  3. Apolipoprotein E3
  4. Lipoproteins (Lipoprotein)
  5. LDL Receptors (LDL Receptor)
  6. Apolipoprotein E2
  7. Cholesterol
  8. Methionine (L-Methionine)
  9. Choline (Choline Chloride)
  10. Non-alcoholic Fatty Liver Disease
Show All >>

Therapies Related to Apolipoprotein E2

  1. Bone Marrow Transplantation (Transplantation, Bone Marrow)
  2. Estrogen Replacement Therapy
  3. Sutures (Suture)
  4. Intraperitoneal Injections

CureHunter Inc. provides medical information and specifically does NOT provide medical advice.
© Copyright 2003-2016 CureHunter Inc., MeSH copyright NLM, Journal Articles copyright original owners.