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beta Catenin Summary

Description: A multi-functional catenin that participates in CELL ADHESION and nuclear signaling. Beta catenin binds CADHERINS and helps link their cytoplasmic tails to the ACTIN in the CYTOSKELETON via ALPHA CATENIN. It also serves as a transcriptional co-activator and downstream component of WNT PROTEIN-mediated SIGNAL TRANSDUCTION PATHWAYS.

Also Known As: beta-Catenin; Catenin, beta

Networked: 4231 relevant articles (49 outcomes, 580 trials/studies) for this Bio-Agent

Key Diseases for which beta Catenin is Relevant

  1. Neoplasms (Cancer) : 20 outcomes 173 studies in 1959 results
  2. Colorectal Neoplasms (Colorectal Cancer) : 7 outcomes 31 studies in 425 results
  3. Adenoma (Adenomas) : 3 outcomes 27 studies in 206 results
  4. Carcinoma (Carcinomatosis) : 2 outcomes 52 studies in 469 results
  5. Neoplasm Metastasis (Metastasis) : 2 outcomes 33 studies in 283 results
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Drugs Related to beta Catenin

  1. Cadherins (E-Cadherin)
  2. Cyclin D1
  3. Messenger RNA (mRNA)
  4. glycogen synthase kinase 3 beta
  5. Transcription Factors (Transcription Factor)
  6. Glycogen Synthase Kinases
  7. Azoxymethane
  8. Dimenhydrinate (DMH)
  9. Sulindac (Copal)
  10. 1,2-Dimethylhydrazine (1,2 Dimethylhydrazine)
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Therapies Related to beta Catenin

  1. Drug Therapy (Chemotherapy)
  2. Chemoprevention
  3. Lasers (Laser)
  4. Therapeutics
  5. Adjuvant Chemotherapy
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