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Clusterin Summary

Description: A highly conserved heterodimeric glycoprotein that is differentially expressed during many severe physiological disturbance states such as CANCER; APOPTOSIS; and various NEUROLOGICAL DISORDERS. Clusterin is ubiquitously expressed and appears to function as a secreted MOLECULAR CHAPERONE.

Also Known As: ApoJ Protein; Apolipoprotein J; Complement Lysis Inhibitor; Complement-Associated Protein SP-40,40; Ionizing Radiation-Induced Protein-8 Show All >>

Networked: 791 relevant articles (21 outcomes, 142 trials/studies) for this Bio-Agent

Key Diseases for which Clusterin is Relevant

  1. Neoplasms (Cancer) : 5 outcomes 32 studies in 221 results
  2. Prostatic Neoplasms (Prostate Cancer) : 3 outcomes 19 studies in 80 results
  3. Neoplasm Metastasis (Metastasis) : 2 outcomes 5 studies in 35 results
  4. Urinary Bladder Neoplasms (Bladder Cancer) : 2 outcomes 5 studies in 15 results
  5. Lung Neoplasms (Lung Cancer) : 2 outcomes 4 studies in 10 results
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Drugs Related to Clusterin

  1. Hormones
  2. Cisplatin (Platino)
  3. Apolipoproteins E (ApoE)
  4. gemcitabine
  5. Zinc
  6. Paclitaxel (Taxol)
  7. Vitronectin
  8. docetaxel (Taxotere)
  9. Retinaldehyde (Retinal)
  10. Calpain
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Therapies Related to Clusterin

  1. Drug Therapy (Chemotherapy)
  2. Heterologous Transplantation (Xenotransplantation)
  3. Intravesical Administration
  4. Castration
  5. Radiotherapy
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