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Proto-Oncogene Proteins c-akt (Protein Kinase B) Summary

Description: A protein-serine-threonine kinase that is activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. It plays a major role in cell metabolism, growth, and survival as a core component of SIGNAL TRANSDUCTION. Three isoforms have been described in mammalian cells.

Also Known As: Protein Kinase B; AKT1 Protein Kinase; AKT2 Protein Kinase; AKT3 Protein Kinase; Akt-alpha Protein Show All >>

Networked: 945 relevant articles (23 outcomes, 62 trials/studies) for this Bio-Agent

Key Diseases for which Proto-Oncogene Proteins c-akt is Relevant

  1. Reperfusion Injury : 5 outcomes in 17 results
  2. Melanoma (Melanoma, Malignant) : 4 outcomes in 34 results
  3. Neoplasms (Cancer) : 3 outcomes 10 studies in 222 results
  4. Myocardial Ischemia (Ischemic Heart Diseases) : 3 outcomes 1 study in 5 results
  5. Insulin Resistance : 2 outcomes 4 studies in 53 results
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Drugs Related to Proto-Oncogene Proteins c-akt

  1. Phosphotransferases (Kinase)
  2. Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
  3. Protein Kinases (Protein Kinase)
  4. Sirolimus (Rapamycin)
  5. Serine (L-Serine)
  6. Insulin (Novolin)
  7. Proteins (Proteins, Gene)
  8. Phosphatidylinositol 3-Kinases
  9. Threonine (L-Threonine)
  10. Insulin Receptor
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Therapies Related to Proto-Oncogene Proteins c-akt

  1. Heterologous Transplantation (Xenotransplantation)
  2. Drug Therapy (Chemotherapy)
  3. Ligation
  4. Ischemic Postconditioning
  5. Angioplasty (Angioplasty, Transluminal)
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