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Phosphoribosylglycinamide Formyltransferase
Summary
19
relevant articles (0 outcomes,
2 trials/studies)
found for this Bio-Agent
Description:
An enzyme that catalyzes the transfer of a formyl group from N10-formyltetrahydrofolate to N1-(5-phospho-D-ribosyl)glycinamide to yield N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and TETRAHYDROFOLATE. It plays a role in the de novo PURINE biosynthetic pathway.
Also Known As:
2-Amino-N-Ribosylacetamide 5'-Phosphate Transformylase; 5'-Phosphoribosylglycinamide Transformylase; GAR Formyltransferase; GAR Transformylase; GARTFase Show All >>
Key Diseases for which Phosphoribosylglycinamide Formyltransferase is
Relevant
-
Neoplasms (Cancer)
:
2 studies in 7 results
-
Leukemia
:
3 results
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Lymphoma (Lymphomas)
:
2 results
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Carcinoma (Carcinomatosis)
:
2 results
-
Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
:
1 result
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Drugs Related to Phosphoribosylglycinamide Formyltransferase
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lometrexol
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Methotrexate (Mexate)
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Thymidylate Synthase
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purine
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folylpolyglutamate synthetase
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Phosphoribosylglycinamide Formyltransferase
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Enzymes
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5,6,7,8-tetrahydrofolic acid (tetrahydrofolate)
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Phosphoribosylaminoimidazolecarboxamide Formyltransferase
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Transferases
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Therapies Related to Phosphoribosylglycinamide Formyltransferase
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Drug Therapy (Chemotherapy)
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