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Stathmin Summary

Description: A ubiquitous phosphoprotein that serves as an intracellular substrate for a variety of SIGNAL TRANSDUCTION PATHWAYS. PHOSPHORYLATION of stathmin occurs during CELL CYCLE progression, and stathmin functions as a microtubule-destabilizing protein that promotes MICROTUBULE depolymerization during INTERPHASE and late MITOSIS. Stathmin is expressed at very high levels in a variety of human CANCERS.

Also Known As: Alpha-Stathmin; Beta-Stathmin; Lap18 Protein; Leukemia-Associated Phosphoprotein p18; Metablastin Show All >>

Networked: 264 relevant articles (11 outcomes, 37 trials/studies) for this Bio-Agent

Key Diseases for which Stathmin is Relevant

  1. Neoplasms (Cancer) : 2 outcomes 14 studies in 112 results
  2. Endometrial Neoplasms (Endometrial Cancer) : 2 outcomes 1 study in 6 results
  3. Breast Neoplasms (Breast Cancer) : 1 outcome 3 studies in 23 results
  4. Stomach Neoplasms (Stomach Cancer) : 1 outcome 3 studies in 6 results
  5. Inflammation : 1 outcome in 3 results
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Drugs Related to Stathmin

  1. Paclitaxel (Taxol)
  2. Small Interfering RNA (siRNA)
  3. docetaxel (Taxotere)
  4. Atrial Natriuretic Factor (ANF)
  5. Tubulin
  6. Messenger RNA (mRNA)
  7. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
  8. Proteins (Proteins, Gene)
  9. Carrier Proteins (Binding Protein)
  10. Complementary DNA (cDNA)
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Therapies Related to Stathmin

  1. Drug Therapy (Chemotherapy)
  2. Heterologous Transplantation (Xenotransplantation)
  3. Axotomy
  4. Lasers (Laser)
  5. Hysterectomy
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