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Laron Syndrome (Syndrome, Laron) Summary

Description: An autosomal recessive disorder characterized by short stature, defective GROWTH HORMONE RECEPTOR, and failure to generate INSULIN-LIKE GROWTH FACTOR I by GROWTH HORMONE. Laron syndrome is not a form of primary pituitary dwarfism (GROWTH HORMONE DEFICIENCY DWARFISM) but the result of mutation of the human GHR gene on chromosome 5.

Also Known As: Syndrome, Laron; Growth Hormone Receptor Defect; Laron Dwarfism; Laron Type Dwarfism I; Primary GH Resistance Show All >>

Networked: 235 relevant articles (2 outcomes, 26 trials/studies) for this Disease

Key Drugs and Agents for Laron Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Insulin-Like Growth Factor I (IGF-1) : 2 outcomes 19 studies in 123 results : IBA
  2. Growth Hormone (Somatotropin) : 4 studies in 75 results : IBA
  3. Somatotropin Receptors (Growth Hormone Receptor) : 2 studies in 58 results : IBA
  4. Insulin (Novolin) : 2 studies in 23 results : FDA 2
  5. Fibrinogen (Factor I) : 2 studies in 4 results : FDA 1
  6. somatotropin-binding protein (growth hormone-binding protein) : 1 study in 16 results : IBA
  7. Hormones : 1 study in 8 results : IBA
  8. Carrier Proteins (Binding Protein) : 1 study in 5 results : IBA
  9. Peptides : 1 study in 2 results : IBA
  10. Dihydrotestosterone (Androstanolone) : 1 study in 1 result : IBA
Show All >>

Diseases Related to Laron Syndrome

  1. Laron Syndrome (Syndrome, Laron)
  2. Multiple Sclerosis
  3. Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
  4. Alzheimer Disease (Alzheimer's Disease)
  5. Obesity
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Key Therapies for Laron Syndrome

Efficacy Chart >>
  1. Subcutaneous Injections : 1 study in 3 results
  2. Transplants (Transplant) : 1 study in 1 result
  3. Injections : 3 results
  4. Tissue Therapy (Cell Therapy) : 2 results
  5. Heterologous Transplantation (Xenotransplantation) : 1 result

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