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DNA Glycosylases (DNA Glycosylase) Summary

Description: A family of DNA repair enzymes that recognize damaged nucleotide bases and remove them by hydrolyzing the N-glycosidic bond that attaches them to the sugar backbone of the DNA molecule. The process called BASE EXCISION REPAIR can be completed by a DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE which excises the remaining RIBOSE sugar from the DNA.

Also Known As: DNA Glycosylase; Methylpurine DNA Glycosylase; DNA Glycosylase, Methylpurine; DNA N glycosidase; Glycosylase, DNA Show All >>

Networked: 180 relevant articles (3 outcomes, 26 trials/studies) for this Bio-Agent

Key Diseases for which DNA Glycosylases is Relevant

  1. Neoplasms (Cancer) : 2 outcomes 2 studies in 41 results
  2. Pneumonia (Pneumonitis) : 1 outcome in 1 result
  3. Lung Neoplasms (Lung Cancer) : 4 studies in 10 results
  4. Breast Neoplasms (Breast Cancer) : 4 studies in 8 results
  5. Pancreatic Neoplasms (Pancreatic Cancer) : 3 studies in 3 results
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Drugs Related to DNA Glycosylases

  1. 8-hydroxyguanine
  2. DNA-(Apurinic or Apyrimidinic Site) Lyase (AP Endonuclease)
  3. Carotenoids (Carotene)
  4. DNA (Deoxyribonucleic Acid)
  5. Purines
  6. Mitochondrial DNA (mtDNA)
  7. Enzymes
  8. Proteins (Proteins, Gene)
  9. Deoxyribonuclease (Pyrimidine Dimer)
  10. A-Form DNA (A-DNA)
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Therapies Related to DNA Glycosylases

  1. Drug Therapy (Chemotherapy)
  2. Photochemotherapy (Photodynamic Therapy)
  3. Lenses
  4. Aftercare (After-Treatment)

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