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Formyl Peptide Receptors (Formyl Peptide Receptor) Summary

Description: A family of G-protein-coupled receptors that was originally identified by its ability to bind N-formyl peptides such as N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE. Since N-formyl peptides are found in MITOCHONDRIA and BACTERIA, this class of receptors is believed to play a role in mediating cellular responses to cellular damage and bacterial invasion. However, non-formylated peptide ligands have also been found for this receptor class.

Also Known As: Formyl Peptide Receptor; Receptors, Formyl Peptide; Chemoattractant Receptor; F-Chemotactic Peptide Receptor; FMLP Receptor Show All >>

Networked: 205 relevant articles (5 outcomes, 16 trials/studies) for this Bio-Agent

Key Diseases for which Formyl Peptide Receptors is Relevant

  1. Asthma (Bronchial Asthma) : 2 outcomes in 16 results
  2. Bacterial Infections (Bacterial Infection) : 1 outcome in 8 results
  3. Rhinitis : 1 outcome in 5 results
  4. Fibrosis (Cirrhosis) : 1 outcome in 2 results
  5. Seasonal Allergic Rhinitis (Hay Fever) : 1 outcome in 1 result
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Drugs Related to Formyl Peptide Receptors

  1. GTP-Binding Proteins (G-Protein)
  2. Annexin A1
  3. ramatroban
  4. Indomethacin (Indometacin)
  5. Trp-Lys-Tyr-Met-Val-Met
  6. 4- butoxy- N- (2- (4- methoxy- phenyl)- 4- oxo- 1,4- dihydro- 2H- quinazolin- 3- yl)- benzamide
  7. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
  8. prostaglandin D2 receptor
  9. Antigens
  10. Chymases (Chymase)
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Therapies Related to Formyl Peptide Receptors

  1. Adjuvant Chemotherapy
  2. Ligation
  3. Drug Therapy (Chemotherapy)
  4. Analgesia

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