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Vascular Endothelial Growth Factor Receptors (VEGF Receptors) Summary

Description: A family of closely related RECEPTOR PROTEIN-TYROSINE KINASES that bind vascular endothelial growth factors. They share a cluster of seven extracellular Ig-like domains which are important for ligand binding. They are highly expressed in vascular endothelial cells and are critical for the physiological and pathological growth, development and maintenance of blood and lymphatic vessels.

Also Known As: VEGF Receptors; Vascular Endothelial Growth Factor Receptor; Receptors, Vascular Endothelial Growth Factor; Endothelial Growth Factor Receptor; Receptor, Endothelial Growth Factors Show All >>

Networked: 2153 relevant articles (90 outcomes, 348 trials/studies) for this Bio-Agent

Key Diseases for which Vascular Endothelial Growth Factor Receptors is Relevant

  1. Neoplasms (Cancer) : 26 outcomes 106 studies in 830 results
  2. Renal Cell Carcinoma (Grawitz Tumor) : 13 outcomes 22 studies in 126 results
  3. Colorectal Neoplasms (Colorectal Cancer) : 7 outcomes 17 studies in 51 results
  4. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) : 7 outcomes 17 studies in 47 results
  5. Glioblastoma (Glioblastoma Multiforme) : 6 outcomes 15 studies in 37 results
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Drugs Related to Vascular Endothelial Growth Factor Receptors

  1. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
  2. Protein-Tyrosine Kinases (Tyrosine Kinase)
  3. Phosphotransferases (Kinase)
  4. Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)
  5. sunitinib (Sutent)
  6. 4- ((4- Fluoro- 2- methyl- 1H- indol- 5- yl)oxy)- 6- methoxy- 7- (3- (pyrrolidin- 1- yl)propoxy)quinazoline (AZD2171)
  7. sorafenib (BAY 43-9006)
  8. Epidermal Growth Factor Receptor (EGF Receptor)
  9. bevacizumab
  10. vatalanib (PTK787)
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Therapies Related to Vascular Endothelial Growth Factor Receptors

  1. Drug Therapy (Chemotherapy)
  2. Radiotherapy
  3. Heterologous Transplantation (Xenotransplantation)
  4. Homologous Transplantation (Allograft)
  5. Combination Drug Therapy (Combination Chemotherapy)
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