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Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule) Summary

158 relevant articles (0 outcomes, 11 trials/studies) found for this Bio-Agent

Description: A member of the immunoglobulin superfamily of neuronal cell adhesion molecules that is required for proper nervous system development. Neural cell adhesion molecule L1 consists of six Ig domains, five fibronectin domains, a transmembrane region and an intracellular domain. Two splicing variants are known: a neuronal form that contains a four-amino acid RSLE sequence in the cytoplasmic domain, and a non-neuronal form that lacks the RSLE sequence. Mutations in the L1 gene result in L1 disease. Neural cell adhesion molecule L1 is predominantly expressed during development in neurons and Schwann cells; involved in cell adhesion, neuronal migration, axonal growth and pathfinding, and myelination.

Also Known As: L1 Cell Adhesion Molecule; CALL Protein; CamL1 Gene Product; Cell Adhesion Molecule L1; Cell Surface Glycoprotein L1 Show All >>

Key Diseases for which Neural Cell Adhesion Molecule L1 is Relevant

  1. Adhesions : 2 studies in 27 results
  2. Hydrocephalus (Hydrocephaly) : 1 study in 52 results
  3. Mental Retardation (Idiocy) : 1 study in 20 results
  4. Fasciculation (Fasciculations) : 1 study in 20 results
  5. Hirschsprung Disease (Hirschsprung's Disease) : 1 study in 8 results
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Drugs Related to Neural Cell Adhesion Molecule L1

  1. Messenger RNA (mRNA)
  2. Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)
  3. methyl N-acetylsibirosaminide (MASA)
  4. Neural Cell Adhesion Molecules (Neural Cell Adhesion Molecule)
  5. Ethanol (Ethyl Alcohol)
  6. Immunoglobulins (Immunoglobulin)
  7. Proteins (Proteins, Gene)
  8. Antibodies
  9. Nerve Growth Factor (NGF)
  10. Complementary DNA (cDNA)
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Therapies Related to Neural Cell Adhesion Molecule L1

  1. Heterologous Transplantation (Xenotransplantation)

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