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70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa) Summary

Description: A family of ribosomal protein S6 kinases that are considered the major physiological kinases for RIBOSOMAL PROTEIN S6. Unlike RIBOSOMAL PROTEIN S6 KINASES, 90KDa the proteins in this family are sensitive to the inhibitory effects of RAPAMYCIN and contain a single kinase domain. They are referred to as 70kDa proteins, however ALTERNATIVE SPLICING of mRNAs for proteins in this class also results in 85kDa variants being formed.

Also Known As: Ribosomal Protein S6 Kinases, 70 kDa; p70s6k; Ribosomal Protein S6 Kinases, 70-kDa; S6 Kinase, p70; p70 S6 Kinase

Networked: 454 relevant articles (13 outcomes, 52 trials/studies) for this Bio-Agent

Key Diseases for which 70-kDa Ribosomal Protein S6 Kinases is Relevant

  1. Neoplasms (Cancer) : 2 outcomes 7 studies in 96 results
  2. Melanoma (Melanoma, Malignant) : 1 outcome 2 studies in 6 results
  3. Tuberous Sclerosis (Bourneville's Disease) : 1 outcome 1 study in 15 results
  4. Lymphangioleiomyomatosis (Lymphangiomyomatosis) : 1 outcome 1 study in 2 results
  5. Parkinson Disease (Parkinson's Disease) : 1 outcome 1 study in 2 results
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Drugs Related to 70-kDa Ribosomal Protein S6 Kinases

  1. Sirolimus (Rapamycin)
  2. Ribosomal Protein S6 Kinases (S6 Kinase)
  3. Curcumin
  4. Quercetin
  5. everolimus
  6. Proto-Oncogene Proteins c-akt (Protein Kinase B)
  7. Glucose (Dextrose)
  8. Proline (L-Proline)
  9. Synucleins
  10. Isoflurane
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Therapies Related to 70-kDa Ribosomal Protein S6 Kinases

  1. Heterologous Transplantation (Xenotransplantation)
  2. Drug Therapy (Chemotherapy)
  3. Ischemic Postconditioning
  4. Resistance Training
  5. Aftercare (After-Treatment)

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