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alpha-Crystallins (alpha-Crystallin) Summary

Description: A subclass of crystallins that provides the majority of refractive power and translucency to the lens (LENS, CRYSTALLINE) in VERTEBRATES. Alpha-crystallins also act as molecular chaperones that bind to denatured proteins, keep them in solution and thereby maintain the translucency of the lens. The proteins exist as large oligomers that are formed from ALPHA-CRYSTALLIN A CHAIN and ALPHA-CRYSTALLIN B CHAIN subunits.

Also Known As: alpha-Crystallin; alpha Crystallin; alpha Crystallins; Crystallins, alpha

Networked: 197 relevant articles (6 outcomes, 17 trials/studies) for this Bio-Agent

Key Diseases for which alpha-Crystallins is Relevant

  1. Cataract (Cataracts) : 5 outcomes 10 studies in 109 results
  2. Inflammation : 1 outcome 2 studies in 4 results
  3. Shock : 2 studies in 31 results
  4. Tuberculosis (Tuberculoses) : 1 study in 8 results
  5. Neurodegenerative Diseases (Neurodegenerative Disease) : 1 study in 6 results
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Drugs Related to alpha-Crystallins

  1. Crystallins (Crystallin)
  2. gamma-Crystallins
  3. Carnosine
  4. Amyloid (Amyloid Fibrils)
  5. Tryptophan (L-Tryptophan)
  6. Molecular Chaperones (Chaperone, Molecular)
  7. Antibodies
  8. Calpain
  9. naphthalene
  10. Zinc
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Therapies Related to alpha-Crystallins

  1. Lenses
  2. Lasers (Laser)
  3. Drug Therapy (Chemotherapy)
  4. Fluid Therapy (Oral Rehydration Therapy)

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