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TATA-Box Binding Protein (TATA-Binding Protein) Summary

Description: A general transcription factor that plays a major role in the activation of eukaryotic genes transcribed by RNA POLYMERASES. It binds specifically to the TATA BOX promoter element, which lies close to the position of transcription initiation in RNA transcribed by RNA POLYMERASE II. Although considered a principal component of TRANSCRIPTION FACTOR TFIID it also takes part in general transcription factor complexes involved in RNA POLYMERASE I and RNA POLYMERASE III transcription.

Also Known As: TATA-Binding Protein; RNA Polymerase II TATA-Binding Protein; Transcription Factor TBP; RNA Polymerase II TATA Binding Protein; TATA Binding Protein Show All >>

Networked: 153 relevant articles (0 outcomes, 12 trials/studies) for this Bio-Agent

Key Diseases for which TATA-Box Binding Protein is Relevant

  1. Spinocerebellar Ataxias (Spinocerebellar Ataxia) : 1 study in 39 results
  2. Infection : 1 study in 12 results
  3. Shock : 1 study in 10 results
  4. Huntington Disease (Huntington's Disease) : 1 study in 3 results
  5. Progressive Myoclonic Epilepsies (Progressive Myoclonic Epilepsy) : 1 study in 2 results
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Drugs Related to TATA-Box Binding Protein

  1. tributyl phosphate (TBP)
  2. Oxidoreductases
  3. Hypoxanthine
  4. Ribosomal Proteins (Ribosomal Protein)
  5. Transferases
  6. Peptidylprolyl Isomerase (Prolyl Isomerase)
  7. Tryptophan (L-Tryptophan)
  8. Cyclophilin A
  9. Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)
  10. Succinate Dehydrogenase (Fumarate Reductase)
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Therapies Related to TATA-Box Binding Protein

  1. Ovariectomy (Oophorectomy)

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