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Systemic Mastocytosis Summary

313 relevant articles (26 outcomes, 22 trials/studies) found for this Disease

Description: A group of disorders caused by the abnormal proliferation of MAST CELLS in a variety of extracutaneous tissues including bone marrow, liver, spleen, lymph nodes, and gastrointestinal tract. Systemic mastocytosis is commonly seen in adults. These diseases are categorized on the basis of clinical features, pathologic findings, and prognosis.

Also Known As: Mastocytosis, Systemic; Aggressive Systemic Mastocytosis; Indolent Systemic Mastocytosis; Aggressive Systemic Mastocytoses; Indolent Systemic Mastocytoses Show All >>

Key Drugs and Agents for Systemic Mastocytosis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. imatinib (Gleevec) : 5 outcomes 1 study in 26 results : FDA 2
  2. Interferon-alpha (Interferon Alfa) : 4 outcomes 1 study in 20 results : FDA 1
  3. Cromolyn Sodium (Cromoglicic Acid) : 3 outcomes 1 study in 10 results : FDA 25 Generic
  4. Venoms : 3 outcomes 1 study in 5 results : IBA
  5. Tryptases (Tryptase) : 1 outcome 1 study in 30 results : IBA
  6. dasatinib (BMS 354825) : 1 outcome 1 study in 4 results : FDA 2
  7. Codon (Codons) : 1 outcome in 15 results : IBA
  8. Protein-Tyrosine Kinases (Tyrosine Kinase) : 1 outcome in 10 results : IBA
  9. Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor) : 1 outcome in 7 results : IBA
  10. Cladribine : 1 outcome in 5 results : FDA 3 Generic
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Diseases Related to Systemic Mastocytosis

  1. Anaphylaxis (Anaphylactic Shock)
  2. Mastocytosis (Mast-Cell Disease)
  3. Myelodysplastic Syndromes (Myelodysplastic Syndrome)
  4. Hypersensitivity (Allergy)
  5. Hypereosinophilic Syndrome (Loeffler Endocarditis)
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Key Therapies for Systemic Mastocytosis

Efficacy Chart >>
  1. Immunotherapy : 5 outcomes 2 studies in 10 results
  2. Splenectomy : 1 outcome in 5 results
  3. Drug Therapy (Chemotherapy) : 1 outcome in 4 results
  4. Combination Drug Therapy (Combination Chemotherapy) : 1 outcome in 2 results
  5. Stem Cell Transplantation : 1 outcome in 1 result
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