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Mitochondrial Diseases (Mitochondrial Disease) Summary

Description: Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes.

Also Known As: Mitochondrial Disease; Respiratory Chain Deficiency; Disorders, Mitochondrial; Mitochondrial Disorders; Mitochondrial Electron Transport Chain Deficiencies Show All >>

Networked: 1636 relevant articles (38 outcomes, 132 trials/studies) for this Disease

Key Drugs and Agents for Mitochondrial Diseases

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Mitochondrial DNA (mtDNA) : 6 outcomes 52 studies in 700 results : IBA
  2. Pyruvic Acid (Pyruvate) : 5 outcomes 3 studies in 31 results : IBA
  3. Lactic Acid : 2 outcomes 4 studies in 66 results : FDA 4 Generic
  4. Biological Markers (Surrogate Marker) : 2 outcomes 2 studies in 15 results : IBA
  5. Enzymes : 2 outcomes 1 study in 34 results : IBA
  6. Vitamins : 2 outcomes 1 study in 10 results : IBA
  7. NAD (NADH) : 2 outcomes 1 study in 10 results : IBA
  8. Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase) : 2 outcomes 1 study in 2 results : IBA
  9. nicotinamide-beta-riboside : 2 outcomes 1 study in 2 results : IBA
  10. Sodium : 2 outcomes in 4 results : IBA
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Diseases Related to Mitochondrial Diseases

  1. Stroke (Strokes)
  2. MELAS Syndrome (Syndrome, MELAS)
  3. Neurodegenerative Diseases (Neurodegenerative Disease)
  4. Liver Failure
  5. Parkinson Disease (Parkinson's Disease)
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Key Therapies for Mitochondrial Diseases

Efficacy Chart >>
  1. Ketogenic Diet : 2 outcomes in 5 results
  2. Intraocular Injections : 1 outcome in 1 result
  3. Exercise Therapy (Therapy, Exercise) : 1 outcome in 1 result
  4. Transplantation (Transplant Recipients) : 1 study in 7 results
  5. Cochlear Implantation : 1 study in 5 results
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