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Familial Amyloid Neuropathies (Familial Amyloid Polyneuropathy) Summary

Description: Inherited disorders of the peripheral nervous system associated with the deposition of AMYLOID in nerve tissue. The different clinical types based on symptoms correspond to the presence of a variety of mutations in several different proteins including transthyretin (PREALBUMIN); APOLIPOPROTEIN A-I; and GELSOLIN.

Also Known As: Familial Amyloid Polyneuropathy; Amyloid Neuropathies, Familial; Amyloid Polyneuropathy, British Type; Amyloid Polyneuropathy, Iowa Type; Amyloid Polyneuropathy, Swiss Type Show All >>

Networked: 446 relevant articles (16 outcomes, 30 trials/studies) for this Disease

Key Drugs and Agents for Familial Amyloid Neuropathies

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Prealbumin (Transthyretin) : 4 outcomes 17 studies in 249 results : IBA
  2. Amyloid (Amyloid Fibrils) : 1 outcome 6 studies in 114 results : IBA
  3. tafamidis : 1 outcome 1 study in 12 results : IBA
  4. Diflunisal (Dolobid) : 1 outcome 1 study in 6 results : FDA 8
  5. Dopamine beta-Hydroxylase : 1 outcome in 2 results : IBA
  6. 3-Iodobenzylguanidine (Iobenguane) : 2 studies in 5 results : IBA
  7. Complementary DNA (cDNA) : 1 study in 2 results : IBA
  8. Small Interfering RNA (siRNA) : 1 study in 1 result : IBA
  9. Genetic Markers (Genetic Marker) : 1 study in 1 result : IBA
  10. gallium citrate : 1 study in 1 result : IBA
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Diseases Related to Familial Amyloid Neuropathies

  1. Polyneuropathies (Polyneuropathy)
  2. Amyloidosis
  3. Cardiomyopathies (Cardiomyopathy)
  4. Orthostatic Hypotension (Postural Hypotension)
  5. Neuralgia (Stump Neuralgia)
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Key Therapies for Familial Amyloid Neuropathies

Efficacy Chart >>
  1. Liver Transplantation : 8 outcomes 2 studies in 93 results
  2. Transplants (Transplant) : 1 outcome 1 study in 25 results
  3. Transplantation (Transplant Recipients) : 1 outcome in 11 results
  4. Therapeutics : 2 studies in 2 results
  5. Sympathectomy (Sympathectomies) : 1 study in 2 results
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