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Tauopathies Summary

Description: Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (TAU PROTEINS) in neurons and glial cells in the brain. Pathological aggregations of tau proteins are associated with mutation of the tau gene on chromosome 17 in patients with ALZHEIMER DISEASE; DEMENTIA; PARKINSONIAN DISORDERS; progressive supranuclear palsy (SUPRANUCLEAR PALSY, PROGRESSIVE); and corticobasal degeneration.

Also Known As: Tauopathy

Networked: 952 relevant articles (31 outcomes, 85 trials/studies) for this Disease

Key Drugs and Agents for Tauopathies

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. tau Proteins (tau Protein) : 4 outcomes 19 studies in 407 results : IBA
  2. Proteins (Proteins, Gene) : 4 outcomes 1 study in 43 results : IBA
  3. Amyloid (Amyloid Fibrils) : 2 outcomes 8 studies in 91 results : IBA
  4. Lithium : 2 outcomes 1 study in 10 results : IBA
  5. Iron : 2 outcomes in 3 results : IBA
  6. Phosphotransferases (Kinase) : 1 outcome 5 studies in 37 results : IBA
  7. Biological Markers (Surrogate Marker) : 1 outcome 3 studies in 11 results : IBA
  8. alpha-Synuclein : 1 outcome 2 studies in 23 results : IBA
  9. Peptides : 1 outcome 1 study in 8 results : IBA
  10. NAPVSIPQ peptide : 1 outcome 1 study in 5 results : IBA
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Diseases Related to Tauopathies

  1. Alzheimer Disease (Alzheimer's Disease)
  2. Tauopathies
  3. Parkinson Disease (Parkinson's Disease)
  4. Frontotemporal Lobar Degeneration (Semantic Dementia)
  5. Frontotemporal Dementia
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Key Therapies for Tauopathies

Efficacy Chart >>
  1. Immunotherapy : 2 outcomes 4 studies in 19 results
  2. Therapeutics : 1 outcome 2 studies in 19 results
  3. Anesthesia : 2 results
  4. Individualized Medicine : 1 result
  5. Tissue Therapy (Cell Therapy) : 1 result
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