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Herpes Simplex Encephalitis (Herpes Encephalitis) Summary

Description: An acute (or rarely chronic) inflammatory process of the brain caused by SIMPLEXVIRUS infections which may be fatal. The majority of infections are caused by human herpesvirus 1 (HERPESVIRUS 1, HUMAN) and less often by human herpesvirus 2 (HERPESVIRUS 2, HUMAN). Clinical manifestations include FEVER; HEADACHE; SEIZURES; HALLUCINATIONS; behavioral alterations; APHASIA; hemiparesis; and COMA. Pathologically, the condition is marked by a hemorrhagic necrosis involving the medial and inferior TEMPORAL LOBE and orbital regions of the FRONTAL LOBE. (From Adams et al., Principles of Neurology, 6th ed, pp751-4)

Also Known As: Herpes Encephalitis; Encephalitis, Herpes; Encephalitis, Herpes Simplex; Acute Necrotizing Encephalitis, Herpetic; Herpes Simplex Meningoencephalitis Show All >>

Networked: 509 relevant articles (35 outcomes, 36 trials/studies) for this Disease

Key Drugs and Agents for Herpes Simplex Encephalitis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Acyclovir (Aciclovir) : 22 outcomes 12 studies in 158 results : FDA 51 Generic
  2. Vidarabine (Vira-A) : 4 outcomes 5 studies in 42 results : FDA 2
  3. Neonatal herpes : 2 outcomes 1 study in 16 results : IBA
  4. Antiviral Agents (Antivirals) : 2 outcomes in 13 results : IBA
  5. DNA (Deoxyribonucleic Acid) : 1 outcome 4 studies in 30 results : IBA
  6. Viral DNA : 1 outcome 1 study in 8 results : IBA
  7. valacyclovir (valaciclovir) : 1 outcome 1 study in 6 results : FDA 12 Generic
  8. styrene-methylmethacrylate copolymer : 1 outcome 1 study in 6 results : IBA
  9. Antigens : 1 outcome in 14 results : IBA
  10. Cytarabine (Cytosar-U) : 1 outcome in 8 results : FDA 13 Generic
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Diseases Related to Herpes Simplex Encephalitis

  1. Infection
  2. Herpes Zoster
  3. Chickenpox
  4. Herpes Genitalis (Genital Herpes)
  5. Encephalitis (Encephalitis, Rasmussen)
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Key Therapies for Herpes Simplex Encephalitis

Efficacy Chart >>
  1. Decompressive Craniectomy : 2 outcomes in 4 results
  2. Intensive Care (Surgical Intensive Care) : 1 outcome 1 study in 3 results
  3. Hyperbaric Oxygenation : 1 outcome in 1 result
  4. General Anesthesia : 1 outcome in 1 result
  5. Electrodes (Electrode) : 1 study in 1 result
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