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Spinocerebellar Ataxias (Spinocerebellar Ataxia) Summary

Description: A group of dominantly inherited, predominately late-onset, cerebellar ataxias which have been divided into multiple subtypes based on clinical features and genetic mapping. Progressive ataxia is a central feature of these conditions, and in certain subtypes POLYNEUROPATHY; DYSARTHRIA; visual loss; and other disorders may develop. (From Joynt, Clinical Neurology, 1997, Ch65, pp 12-17; J Neuropathol Exp Neurol 1998 Jun;57(6):531-43)

Also Known As: Spinocerebellar Ataxia; Spinocerebellar Ataxia Type 6; Spinocerebellar Atrophy; Dominantly-Inherited Spinocerebellar Ataxias; Spinocerebellar Ataxia-1 Show All >>

Networked: 1009 relevant articles (20 outcomes, 54 trials/studies) for this Disease

Key Drugs and Agents for Spinocerebellar Ataxias

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. varenicline (Chantix) : 2 outcomes 1 study in 2 results : FDA 1
  2. polyglutamine : 1 outcome 13 studies in 367 results : IBA
  3. Proteins (Proteins, Gene) : 1 outcome 4 studies in 64 results : IBA
  4. Staphylococcal Protein A (A, Protein) : 1 outcome 2 studies in 21 results : IBA
  5. ataxin-7 : 1 outcome 1 study in 39 results : IBA
  6. Nicotinic Receptors (Nicotinic Acetylcholine Receptor) : 1 outcome 1 study in 1 result : IBA
  7. Choline (Choline Chloride) : 1 outcome 1 study in 1 result : IBA
  8. tyrosyl-DNA phosphodiesterase : 1 outcome in 9 results : IBA
  9. Carbon Monoxide : 1 outcome in 6 results : IBA
  10. Nuclear Proteins (Protein, Nuclear) : 1 outcome in 5 results : IBA
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Diseases Related to Spinocerebellar Ataxias

  1. Neurodegenerative Diseases (Neurodegenerative Disease)
  2. Ataxia (Dyssynergia)
  3. Huntington Disease (Huntington's Disease)
  4. Alzheimer Disease (Alzheimer's Disease)
  5. Machado-Joseph Disease (Spinocerebellar Ataxia Type 3)
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Key Therapies for Spinocerebellar Ataxias

Efficacy Chart >>
  1. Electrodes (Electrode) : 1 outcome 1 study in 2 results
  2. Mesenchymal Stem Cell Transplantation : 1 outcome in 1 result
  3. Radiotherapy : 1 outcome in 1 result
  4. Injections : 1 outcome in 1 result
  5. Occupational Therapy (Therapy, Occupational) : 1 study in 1 result
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