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Parkinsonian Disorders (Parkinsonism) Summary

Description: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.

Also Known As: Parkinsonism; Ramsay Hunt Paralysis Syndrome; Autosomal Dominant Juvenile Parkinson Disease; Autosomal Dominant Juvenile Parkinsonism; Autosomal Dominant Parkinsonism Show All >>

Networked: 6267 relevant articles (319 outcomes, 640 trials/studies) for this Disease

Key Drugs and Agents for Parkinsonian Disorders

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Levodopa (L Dopa) : 93 outcomes 107 studies in 1295 results : FDA 31 Generic
  2. Dopamine (Intropin) : 27 outcomes 47 studies in 533 results : FDA 36 Generic
  3. 1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP) : 14 outcomes 72 studies in 642 results : IBA
  4. Amantadine (Aman) : 10 outcomes 3 studies in 127 results : FDA 20 Generic
  5. Bromocriptine (Parlodel) : 9 outcomes 8 studies in 61 results : FDA 8 Generic
  6. Selegiline (E250) : 6 outcomes 34 studies in 84 results : FDA 17 Generic
  7. Antipsychotic Agents (Antipsychotics) : 6 outcomes 21 studies in 206 results : IBA
  8. Haloperidol (Haldol) : 6 outcomes 15 studies in 98 results : FDA 107 Generic
  9. olanzapine (Zyprexa) : 6 outcomes 5 studies in 40 results : FDA 13
  10. levodopa drug combination carbidopa (Nakom) : 6 outcomes 2 studies in 35 results : FDA 3 Generic
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Diseases Related to Parkinsonian Disorders

  1. Dyskinesias (Dyskinesia)
  2. Parkinson Disease (Parkinson's Disease)
  3. Tremor (Tremors)
  4. Movement Disorders (Movement Disorder)
  5. Dementia (Dementias)
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Key Therapies for Parkinsonian Disorders

Efficacy Chart >>
  1. Pallidotomy : 8 outcomes 1 study in 27 results
  2. Deep Brain Stimulation : 6 outcomes 8 studies in 71 results
  3. Transplants (Transplant) : 6 outcomes 7 studies in 46 results
  4. Activities of Daily Living (ADL) : 4 outcomes 5 studies in 25 results
  5. Transplantation (Transplant Recipients) : 4 outcomes 4 studies in 36 results
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