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Experimental Autoimmune Myasthenia Gravis (Autoimmune Experimental Myasthenia Gravis) Summary

Description: Any autoimmune animal disease model used in the study of MYASTHENIA GRAVIS. Injection with purified neuromuscular junction acetylcholine receptor (AChR) (see RECEPTORS, CHOLINERGIC) components results in a myasthenic syndrome that has acute and chronic phases. The motor endplate pathology, loss of acetylcholine receptors, presence of circulating anti-AChR antibodies, and electrophysiologic changes make this condition virtually identical to human myasthenia gravis. Passive transfer of AChR antibodies or lymphocytes from afflicted animals to normals induces passive transfer experimental autoimmune myasthenia gravis. (From Joynt, Clinical Neurology, 1997, Ch 54, p3)

Also Known As: Autoimmune Experimental Myasthenia Gravis; Myasthenia Gravis, Autoimmune, Experimental; Experimental Autoimmune Myasthenia Gravis, Passive Transfer; Experimental Myasthenia; Experimental Myasthenia Gravis Show All >>

Networked: 436 relevant articles (16 outcomes, 36 trials/studies) for this Disease

Key Drugs and Agents for Experimental Autoimmune Myasthenia Gravis

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Drugs and Important Biological Agents (IBA) related to treatments:
  1. Acetylcholine (Acetylcholine Chloride) : 3 outcomes 11 studies in 211 results : FDA 2
  2. Autoantibodies : 2 outcomes 1 study in 14 results : IBA
  3. Nicotinic Receptors (Nicotinic Acetylcholine Receptor) : 1 outcome 1 study in 29 results : IBA
  4. Immunosuppressive Agents (Immunosuppressants) : 1 outcome 1 study in 2 results : IBA
  5. Cholinesterase Inhibitors (Anticholinesterases) : 1 outcome 1 study in 2 results : IBA
  6. Chaperonin 60 : 1 outcome 1 study in 1 result : IBA
  7. Interleukin-9 (Interleukin 9) : 1 outcome 1 study in 1 result : IBA
  8. Peptide Fragments : 1 outcome 1 study in 1 result : IBA
  9. Glutamate Decarboxylase (Decarboxylase, Glutamate) : 1 outcome 1 study in 1 result : IBA
  10. Peptides : 1 outcome in 14 results : IBA
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Diseases Related to Experimental Autoimmune Myasthenia Gravis

  1. Myasthenia Gravis
  2. Autoimmune Diseases (Autoimmune Disease)
  3. Type 1 Diabetes Mellitus (Autoimmune Diabetes)
  4. Muscle Weakness
  5. Meningeal Carcinomatosis
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Key Therapies for Experimental Autoimmune Myasthenia Gravis

Efficacy Chart >>
  1. Intraperitoneal Injections : 1 outcome 1 study in 1 result
  2. Lymphatic Irradiation : 1 outcome in 2 results
  3. Immunotherapy : 1 study in 11 results
  4. Immunomodulation : 1 study in 3 results
  5. Thymectomy : 1 study in 2 results
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