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Duchenne Muscular Dystrophy
(Muscular Dystrophy, Becker)
Summary
2622
relevant articles (52 outcomes,
220 trials/studies)
found for this Disease
Description:
An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)
Also Known As:
Muscular Dystrophy, Becker; Becker Muscular Dystrophy; Dystrophy, Duchenne Muscular; Muscular Dystrophy, Duchenne; Childhood Muscular Dystrophy, Pseudohypertrophic Show All >>
Key Drugs and Agents for Duchenne Muscular Dystrophy
Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
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Dystrophin
:
13 outcomes 53 studies in 1202 results
: IBA
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Creatine Kinase (Creatine Phosphokinase)
:
6 outcomes 7 studies in 135 results
: IBA
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Prednisone (Sone)
:
2 outcomes 8 studies in 28 results
:
FDA 118
Generic
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Utrophin
:
2 outcomes 5 studies in 77 results
: IBA
-
Prednisolone (Predate)
:
2 outcomes 3 studies in 13 results
:
FDA 54
Generic
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Mazindol (Mazanor)
:
2 outcomes 2 studies in 7 results
:
FDA 2
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Growth Hormone (Somatotropin)
:
2 outcomes 1 study in 12 results
: IBA
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Glycoproteins (Glycoprotein)
:
2 outcomes in 32 results
: IBA
-
Human Growth Hormone (Saizen)
:
2 outcomes in 5 results
:
FDA 15
Generic
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Complementary DNA (cDNA)
:
1 outcome 6 studies in 81 results
: IBA
Show All >>
Diseases Related to Duchenne Muscular Dystrophy
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Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker)
-
Muscular Dystrophies (Muscular Dystrophy)
-
Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy)
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Muscular Diseases (Myopathy)
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Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
Show All >>
Key Therapies for Duchenne Muscular Dystrophy
Efficacy Chart >>
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Transplantation (Transplant Recipients)
:
1 outcome 3 studies in 45 results
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Transplants (Transplant)
:
1 outcome 2 studies in 6 results
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Intermittent Positive-Pressure Ventilation
:
1 outcome 1 study in 8 results
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Immunotherapy
:
1 outcome 1 study in 2 results
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Tissue Therapy (Cell Therapy)
:
1 outcome in 7 results
Show All >>
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