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Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) Summary

Description: An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)

Also Known As: Muscular Dystrophy, Becker; Becker Muscular Dystrophy; Dystrophy, Duchenne Muscular; Muscular Dystrophy, Duchenne; Childhood Muscular Dystrophy, Pseudohypertrophic Show All >>

Networked: 3772 relevant articles (89 outcomes, 333 trials/studies) for this Disease

Key Drugs and Agents for Duchenne Muscular Dystrophy

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Dystrophin : 17 outcomes 89 studies in 1834 results : IBA
  2. Creatine Kinase (Creatine Phosphokinase) : 6 outcomes 8 studies in 134 results : IBA
  3. Prednisolone (Predate) : 4 outcomes 5 studies in 22 results : FDA 55 Generic
  4. Prednisone (Sone) : 3 outcomes 12 studies in 38 results : FDA 119 Generic
  5. Adrenal Cortex Hormones (Corticosteroids) : 3 outcomes 5 studies in 30 results : IBA
  6. Growth Hormone (Somatotropin) : 3 outcomes 2 studies in 13 results : IBA
  7. Utrophin : 2 outcomes 8 studies in 110 results : IBA
  8. Proteins (Proteins, Gene) : 2 outcomes 6 studies in 68 results : IBA
  9. Steroids : 2 outcomes 4 studies in 29 results : IBA
  10. RNA Precursors (Precursor, mRNA) : 2 outcomes 4 studies in 16 results : IBA
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Diseases Related to Duchenne Muscular Dystrophy

  1. Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker)
  2. Muscular Dystrophies (Muscular Dystrophy)
  3. Cardiomyopathies (Cardiomyopathy)
  4. Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy)
  5. Cystic Fibrosis (Mucoviscidosis)
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Key Therapies for Duchenne Muscular Dystrophy

Efficacy Chart >>
  1. Artificial Respiration (Mechanical Ventilation) : 4 outcomes 3 studies in 29 results
  2. Transplantation (Transplant Recipients) : 2 outcomes 5 studies in 63 results
  3. Tissue Therapy (Cell Therapy) : 1 outcome 1 study in 13 results
  4. Therapeutics : 1 outcome 1 study in 13 results
  5. Intermittent Positive-Pressure Ventilation : 1 outcome 1 study in 10 results
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