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Limbic Encephalitis (Paraneoplastic Limbic Encephalitis) Summary

Description: A paraneoplastic syndrome marked by degeneration of neurons in the medial temporal lobe. Clinical features include behavioral changes, HALLUCINATIONS, loss of short term memory, anosmia, AGEUSIA, and DEMENTIA. Circulating anti-neuronal antibodies (anti-Hu; also called ANNA 1) and small cell lung carcinomas are frequently associated with this condition. (From Pathologe 1997 Sep;18(5):406-10; J Int Neuropsychol Soc 1996 Sep;2(5):460-6; Brain 1997 Jun;120(Pt 6):923-8)

Also Known As: Paraneoplastic Limbic Encephalitis; Encephalitis, Limbic; Encephalitides, Paraneoplastic Limbic; Encephalitis, Paraneoplastic Limbic; Limbic Encephalitis, Paraneoplastic

Networked: 426 relevant articles (15 outcomes, 11 trials/studies) for this Disease

Key Drugs and Agents for Limbic Encephalitis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Antibodies : 4 outcomes 8 studies in 218 results : IBA
  2. Steroids : 2 outcomes 1 study in 4 results : IBA
  3. Potassium Channels (Potassium Channel) : 1 outcome 1 study in 17 results : IBA
  4. DNA (Deoxyribonucleic Acid) : 1 outcome 1 study in 6 results : IBA
  5. Voltage-Gated Potassium Channels (Voltage-Gated Potassium Channel) : 1 outcome in 80 results : IBA
  6. Glutamate Decarboxylase (Decarboxylase, Glutamate) : 1 outcome in 25 results : IBA
  7. Opsoclonus myoclonus : 1 outcome in 14 results : IBA
  8. Prednisolone (Predate) : 1 outcome in 3 results : FDA 55 Generic
  9. Methylprednisolone : 1 outcome in 3 results : FDA 18 Generic
  10. Immunoglobulins (Immunoglobulin) : 1 outcome in 3 results : IBA
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Diseases Related to Limbic Encephalitis

  1. Small Cell Lung Carcinoma (Small Cell Lung Cancer)
  2. Neoplasms (Cancer)
  3. Seizures (Seizure)
  4. Encephalitis (Encephalitis, Rasmussen)
  5. Stiff-Person Syndrome (Stiff Man Syndrome)
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Key Therapies for Limbic Encephalitis

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 4 outcomes in 9 results
  2. Immunotherapy : 1 outcome in 22 results
  3. Thymectomy : 1 outcome in 3 results
  4. Radiotherapy : 1 outcome in 2 results
  5. Transplants (Transplant) : 11 results
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