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Intracranial Vasospasm Summary

Description: Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN).

Also Known As: Vasospasm, Intracranial; Cerebral Angiospasm; Cerebral Artery Spasm; Cerebrovascular Spasm; Intracranial Angiospasm Show All >>

Networked: 1495 relevant articles (143 outcomes, 255 trials/studies) for this Disease

Key Drugs and Agents for Intracranial Vasospasm

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Nimodipine (Modus) : 18 outcomes 21 studies in 119 results : FDA 4 Generic
  2. Nicardipine (Dagan) : 8 outcomes 6 studies in 40 results : FDA 15 Generic
  3. Tissue Plasminogen Activator (Alteplase) : 6 outcomes 6 studies in 19 results : FDA 2
  4. Papaverine : 5 outcomes 2 studies in 69 results : IBA
  5. Milrinone (Primacor) : 5 outcomes 2 studies in 14 results : FDA 20 Generic
  6. Calcium : 4 outcomes 3 studies in 54 results : IBA
  7. Endothelin Receptors (Endothelin Receptor) : 4 outcomes 3 studies in 15 results : IBA
  8. Simvastatin (Zocor) : 3 outcomes 7 studies in 10 results : FDA 20 Generic
  9. tirilazad : 3 outcomes 4 studies in 9 results : IBA
  10. Calcium Channels (Calcium Channel) : 3 outcomes 2 studies in 16 results : IBA
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Diseases Related to Intracranial Vasospasm

  1. Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage)
  2. Ischemia
  3. Hemorrhage
  4. Aneurysm (Aneurysms)
  5. Brain Ischemia (Cerebral Ischemia)
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Key Therapies for Intracranial Vasospasm

Efficacy Chart >>
  1. Balloon Angioplasty : 5 outcomes 2 studies in 34 results
  2. Hemodilution : 3 outcomes in 14 results
  3. Angioplasty (Angioplasty, Transluminal) : 2 outcomes 3 studies in 40 results
  4. Intra-Arterial Infusions : 2 outcomes 2 studies in 25 results
  5. Counterpulsation (External Counterpulsation) : 2 outcomes 1 study in 5 results
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