Search Login Register

Optic Nerve Injuries Summary

Description: Injuries to the optic nerve induced by a trauma to the face or head. These may occur with closed or penetrating injuries. Relatively minor compression of the superior aspect of orbit may also result in trauma to the optic nerve. Clinical manifestations may include visual loss, PAPILLEDEMA, and an afferent pupillary defect.

Also Known As: Cranial Nerve II Injuries; Optic Nerve Avulsion; Optic Nerve Contusion; Optic Nerve Transection; Second Cranial Nerve Injuries Show All >>

Networked: 543 relevant articles (34 outcomes, 56 trials/studies) for this Disease

Key Drugs and Agents for Optic Nerve Injuries

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Methylprednisolone : 5 outcomes 2 studies in 16 results : FDA 18 Generic
  2. Ciliary Neurotrophic Factor (CNTF) : 3 outcomes 1 study in 15 results : IBA
  3. Caspase 3 (Caspase-3) : 2 outcomes 1 study in 4 results : IBA
  4. Dexamethasone (Maxidex) : 2 outcomes 1 study in 3 results : FDA 77 Generic
  5. benzoylcarbonyl- aspartyl- glutamyl- valyl- aspartyl- fluoromethyl ketone : 2 outcomes 1 study in 2 results : IBA
  6. Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) : 2 outcomes in 6 results : IBA
  7. Erythropoietin : 2 outcomes in 4 results : FDA 1
  8. Kainic Acid (Kainate) : 2 outcomes in 3 results : IBA
  9. Brain-Derived Neurotrophic Factor (BDNF) : 1 outcome 4 studies in 32 results : IBA
  10. Mannitol (Osmitrol) : 1 outcome 1 study in 2 results : FDA 28 Generic
Show All >>

Diseases Related to Optic Nerve Injuries

  1. Retinal Degeneration
  2. Ischemia
  3. Spinal Cord Injuries (Spinal Cord Injury)
  4. Blindness (Hysterical Blindness)
  5. Ganglion Cysts (Ganglion)
Show All >>

Key Therapies for Optic Nerve Injuries

Efficacy Chart >>
  1. Decompression : 8 outcomes 3 studies in 75 results
  2. Transplantation (Transplant Recipients) : 2 outcomes 1 study in 11 results
  3. Intravitreal Injections : 1 outcome 2 studies in 12 results
  4. Surgical Decompression : 1 outcome 1 study in 8 results
  5. Axotomy : 2 studies in 10 results
Show All >>

CureHunter Inc. provides medical information and specifically does NOT provide medical advice.
© Copyright 2003-2016 CureHunter Inc., MeSH copyright NLM, Journal Articles copyright original owners.