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Activated Protein C Resistance (APC Resistance) Summary

Description: A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.

Also Known As: APC Resistance; Resistance, APC

Networked: 1122 relevant articles (14 outcomes, 97 trials/studies) for this Disease

Key Drugs and Agents for Activated Protein C Resistance

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. factor V Leiden : 8 outcomes 30 studies in 427 results : IBA
  2. Factor V (Coagulation Factor V) : 8 outcomes 15 studies in 276 results : IBA
  3. Prothrombin (Factor II) : 3 outcomes 4 studies in 142 results : IBA
  4. Protein C : 2 outcomes 26 studies in 502 results : IBA
  5. Protein S : 2 outcomes 10 studies in 241 results : IBA
  6. DNA (Deoxyribonucleic Acid) : 2 outcomes 2 studies in 35 results : IBA
  7. Thrombin : 1 outcome 7 studies in 75 results : FDA 2
  8. Lupus Coagulation Inhibitor (Lupus Anticoagulant) : 1 outcome 1 study in 80 results : IBA
  9. Anticoagulants : 1 outcome 1 study in 24 results : IBA
  10. A-factor (Streptomyces) : 1 outcome 1 study in 21 results : IBA
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Diseases Related to Activated Protein C Resistance

  1. Venous Thromboembolism
  2. Thrombosis (Thrombus)
  3. Venous Thrombosis (Deep-Vein Thrombosis)
  4. Thrombophilia
  5. Protein S Deficiency (Deficiency, Protein S)
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Key Therapies for Activated Protein C Resistance

Efficacy Chart >>
  1. Hormone Replacement Therapy (Therapy, Hormone Replacement) : 2 studies in 6 results
  2. Transplants (Transplant) : 1 study in 6 results
  3. Intrauterine Devices (Intrauterine Device) : 1 study in 1 result
  4. Liver Transplantation : 10 results
  5. Transplantation (Transplant Recipients) : 4 results
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