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Cyclin D1 Summary

Description: Protein encoded by the bcl-1 gene which plays a critical role in regulating the cell cycle. Overexpression of cyclin D1 is the result of bcl-1 rearrangement, a t(11;14) translocation, and is implicated in various neoplasms.

Also Known As: Proto-Oncogene Products bcl-1; Proto-Oncogene Protein bcl-1; bcl-1 Proto-Oncogene Products; bcl1 Proto-Oncogene Proteins; Proto Oncogene Products bcl 1 Show All >>

Networked: 4720 relevant articles (81 outcomes, 658 trials/studies) for this Bio-Agent

Key Diseases for which Cyclin D1 is Relevant

  1. Neoplasms (Cancer) : 41 outcomes 177 studies in 2027 results
  2. Breast Neoplasms (Breast Cancer) : 8 outcomes 64 studies in 491 results
  3. Retinoblastoma (Glioblastoma, Retinal) : 5 outcomes 14 studies in 189 results
  4. Squamous Cell Carcinoma (Epidermoid Carcinoma) : 4 outcomes 44 studies in 239 results
  5. Neoplasm Metastasis (Metastasis) : 4 outcomes 18 studies in 255 results
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Drugs Related to Cyclin D1

  1. Phosphotransferases (Kinase)
  2. Cyclins
  3. Cyclin D3
  4. Retinoblastoma Protein
  5. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
  6. Proteins (Proteins, Gene)
  7. Messenger RNA (mRNA)
  8. DNA (Deoxyribonucleic Acid)
  9. NF-kappa B (NF-kB)
  10. Matrix Metalloproteinase 9 (Gelatinase B)
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Therapies Related to Cyclin D1

  1. Heterologous Transplantation (Xenotransplantation)
  2. Drug Therapy (Chemotherapy)
  3. Chemoprevention
  4. Oral Administration
  5. Intraperitoneal Injections
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