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Miller Fisher Syndrome (Fisher Syndrome) Summary

Description: A variant of the GUILLAIN-BARRE SYNDROME characterized by the acute onset of oculomotor dysfunction, ataxia, and loss of deep tendon reflexes with relative sparing of strength in the extremities and trunk. The ataxia is produced by peripheral sensory nerve dysfunction and not by cerebellar injury. Facial weakness and sensory loss may also occur. The process is mediated by autoantibodies directed against a component of myelin found in peripheral nerves. (Adams et al., Principles of Neurology, 6th ed, p1313; Neurology 1987 Sep;37(9):1493-8)

Also Known As: Fisher Syndrome; Syndrome, Miller Fisher; Guillain-Barre Syndrome, Miller Fisher Variant; Miller Fisher Variant of Guillain Barre Syndrome; Miller-Fisher Syndrome Show All >>

Networked: 304 relevant articles (7 outcomes, 18 trials/studies) for this Disease

Key Drugs and Agents for Miller Fisher Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Intravenous Immunoglobulins (IVIG) : 3 outcomes 2 studies in 14 results : FDA 1
  2. Antibodies : 2 outcomes 4 studies in 136 results : IBA
  3. Immunoglobulins (Immunoglobulin) : 2 outcomes 1 study in 15 results : IBA
  4. Immunoglobulin G (IgG) : 1 outcome 5 studies in 76 results : IBA
  5. Gangliosides : 1 outcome 1 study in 23 results : IBA
  6. Steroids : 1 outcome in 1 result : IBA
  7. Adrenal Cortex Hormones (Corticosteroids) : 1 outcome in 1 result : IBA
  8. Autoantibodies : 1 study in 10 results : IBA
  9. Antigens : 1 study in 10 results : IBA
  10. Lipopolysaccharides : 1 study in 8 results : IBA
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Diseases Related to Miller Fisher Syndrome

  1. Ophthalmoplegia (External Ophthalmoplegia)
  2. Encephalitis (Encephalitis, Rasmussen)
  3. Ataxia (Dyssynergia)
  4. Gastroenteritis
  5. Infection
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Key Therapies for Miller Fisher Syndrome

Efficacy Chart >>
  1. Plasma Exchange : 2 outcomes 1 study in 10 results
  2. Immunotherapy : 1 outcome 2 studies in 3 results
  3. Plasmapheresis : 1 outcome 1 study in 18 results
  4. Immunomodulation : 1 study in 1 result
  5. Aftercare (After-Treatment) : 2 results
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