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Simvastatin (Zocor) Summary

Description: A derivative of LOVASTATIN and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL RECEPTORS, it increases breakdown of LDL CHOLESTEROL.

Also Known As: Zocor; MK-733; Synvinolin; MK 733; MK733

Networked: 3176 relevant articles (350 outcomes, 1053 trials/studies) for this Drug

Key Diseases for which Simvastatin is Relevant

  1. Hypercholesterolemia : 51 outcomes 147 studies in 446 results
  2. Hyperlipidemias (Hyperlipidemia) : 22 outcomes 39 studies in 146 results
  3. Dyslipidemias (Dyslipidemia) : 21 outcomes 41 studies in 120 results
  4. Atherosclerosis : 16 outcomes 57 studies in 141 results
  5. Inflammation : 16 outcomes 48 studies in 192 results
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Drugs Related to Simvastatin

  1. atorvastatin (Lipitor)
  2. ezetimibe (Zetia)
  3. Cholesterol
  4. Pravastatin (Pravachol)
  5. LDL Cholesterol
  6. rosuvastatin (Crestor)
  7. Lovastatin (Mevacor)
  8. Fenofibrate (CiL)
  9. Lipoproteins (Lipoprotein)
  10. simvastatin drug combination ezetimibe (Vytorin)
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Therapies Related to Simvastatin

  1. Continuous Ambulatory Peritoneal Dialysis (CAPD)
  2. Drug Therapy (Chemotherapy)
  3. Renal Dialysis (Hemodialysis)
  4. Transplantation (Transplant Recipients)
  5. Ligation
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