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Disintegrins Summary

Description: A family of polypeptides purified from snake venoms, which contain the arginine-glycine-aspartic acid (RGD) sequence. The RGD tripeptide binds to integrin receptors and thus competitively inhibits normal integrin-ligand interactions. Disintegrins thus block adhesive functions and act as platelet aggregation inhibitors.

Key Diseases for which Disintegrins is Relevant

  1. Retinal Detachment (Retinal Detachments) : 1 outcome 1 study in 1 result
  2. Melanoma (Melanoma, Malignant) : 1 outcome in 2 results
  3. Neoplasms (Cancer) : 2 studies in 18 results
  4. Infection : 1 study in 2 results
  5. Carcinoma (Carcinomatosis) : 1 study in 2 results
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Drugs Related to Disintegrins

  1. Fluorescein-5-isothiocyanate (FITC)
  2. Fluorescein (Funduscein)
  3. albolabrin
  4. isothiocyanic acid
  5. Integrins
  6. Viper Venoms (Viper Venom)
  7. echistatin
  8. Proteins (Proteins, Gene)
  9. Matrix Metalloproteinases
  10. Molecular Probes (Molecular Probe)
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Therapies Related to Disintegrins

  1. Therapeutics

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