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Port-Wine Stain (Nevus Flammeus) Summary

Description: A vascular malformation of developmental origin characterized pathologically by ectasia of superficial dermal capillaries, and clinically by persistent macular erythema. In the past, port wine stains have frequently been termed capillary hemangiomas, which they are not; unfortunately this confusing practice persists: HEMANGIOMA, CAPILLARY is neoplastic, a port-wine stain is non-neoplastic. Port-wine stains vary in color from fairly pale pink to deep red or purple and in size from a few millimeters to many centimeters in diameter. The face is the most frequently affected site and they are most often unilateral. (From Rook et al., Textbook of Dermatology, 5th ed, p483)

Also Known As: Nevus Flammeus; Port Wine Stain; Port-Wine Stains; Stain, Port-Wine; Stains, Port-Wine

Networked: 684 relevant articles (86 outcomes, 62 trials/studies) for this Disease

Key Drugs and Agents for Port-Wine Stain

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Argon : 6 outcomes 7 studies in 78 results : IBA
  2. 1-phenyl-3,3-dimethyltriazene (PDT) : 4 outcomes 9 studies in 34 results : IBA
  3. EMLA : 2 outcomes 1 study in 4 results : FDA 3 Generic
  4. glucuronyl glucosamine glycan sulfate (Vessel) : 1 outcome 2 studies in 20 results : IBA
  5. Hemoglobins (Hemoglobin) : 1 outcome 1 study in 4 results : IBA
  6. latanoprost (Xalatan) : 1 outcome 1 study in 1 result : FDA 3
  7. Collagen : 1 outcome in 2 results : IBA
  8. Indocyanine Green (Cardio-Green) : 1 outcome in 1 result : FDA 3 Generic
  9. alexandrite : 1 outcome in 1 result : IBA
  10. bleomycetin : 1 outcome in 1 result : IBA
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Diseases Related to Port-Wine Stain

  1. Hemangioma (Angioma)
  2. Cicatrix (Scar)
  3. Telangiectasis (Telangiectasia)
  4. Vascular Malformations
  5. Pain (Aches)
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Key Therapies for Port-Wine Stain

Efficacy Chart >>
  1. Dye Lasers : 48 outcomes 23 studies in 269 results
  2. Lasers (Laser) : 27 outcomes 25 studies in 282 results
  3. Laser Therapy (Surgery, Laser) : 8 outcomes 3 studies in 78 results
  4. Photochemotherapy (Photodynamic Therapy) : 4 outcomes 8 studies in 40 results
  5. Solid-State Lasers : 3 outcomes 1 study in 23 results
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