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Phosphatidylinositol 4,5-Diphosphate (Phosphatidylinositol 4,5 Diphosphate) Summary

Description: A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase C, with the consequent formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase. (Kendrew, The Encyclopedia of Molecular Biology, 1994)

Also Known As: Phosphatidylinositol 4,5 Diphosphate; Phosphatidylinositol 4,5-Biphosphate; Phosphatidylinositol Phosphate, PtdIns(4,5)P2; Phosphatidylinositol-4,5-Biphosphate; PtIns 4,5-P2 Show All >>

Networked: 26 relevant articles (0 outcomes, 2 trials/studies) for this Bio-Agent

Key Diseases for which Phosphatidylinositol 4,5-Diphosphate is Relevant

  1. Neuroblastoma : 1 study in 2 results
  2. Neurodegenerative Diseases (Neurodegenerative Disease) : 1 study in 1 result
  3. Neoplasms (Cancer) : 6 results
  4. Oculocerebrorenal Syndrome (Lowe Syndrome) : 3 results
  5. Cysts : 2 results
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Drugs Related to Phosphatidylinositol 4,5-Diphosphate

  1. Phosphatidylinositols (Phosphatidylinositol)
  2. phosphatidylinositol 3,4,5-triphosphate
  3. Insulin (Novolin)
  4. Inositol (Myoinositol)
  5. Phosphatidylinositol 4,5-Diphosphate (Phosphatidylinositol 4,5 Diphosphate)
  6. Type C Phospholipases
  7. PTEN Phosphohydrolase (PTEN Phosphatase)
  8. Dynamins (Dynamin)
  9. CD3 Antigens (CD3 Complex)
  10. Staphylococcal Protein A (A, Protein)
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Therapies Related to Phosphatidylinositol 4,5-Diphosphate


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