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Iron Overload Summary

Description: An excessive accumulation of iron in the body due to a greater than normal absorption of iron from the gastrointestinal tract or from parenteral injection. This may arise from idiopathic hemochromatosis, excessive iron intake, chronic alcoholism, certain types of refractory anemia, or transfusional hemosiderosis. (From Churchill's Illustrated Medical Dictionary, 1989)

Also Known As: Overload, Iron

Networked: 4762 relevant articles (224 outcomes, 517 trials/studies) for this Disease

Key Drugs and Agents for Iron Overload

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Iron : 112 outcomes 261 studies in 2743 results : IBA
  2. Deferoxamine (Desferal) : 36 outcomes 37 studies in 393 results : FDA 5 Generic
  3. deferasirox : 29 outcomes 35 studies in 193 results : FDA 1
  4. Chelating Agents : 22 outcomes 13 studies in 175 results : IBA
  5. deferiprone (CP20) : 20 outcomes 25 studies in 146 results : IBA
  6. Ferritins (Ferritin) : 19 outcomes 83 studies in 708 results : IBA
  7. Isoflurophate (DFP) : 6 outcomes 3 studies in 21 results : FDA 1
  8. Transferrin (beta 2 Transferrin) : 5 outcomes 39 studies in 338 results : IBA
  9. Hemoglobins (Hemoglobin) : 3 outcomes 4 studies in 48 results : IBA
  10. Ribavirin (Virazole) : 3 outcomes 1 study in 12 results : FDA 16 Generic
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Diseases Related to Iron Overload

  1. beta-Thalassemia (Cooley's Anemia)
  2. Hemochromatosis (Bronze Diabetes)
  3. Anemia
  4. Thalassemia
  5. Sickle Cell Anemia (Hemoglobin S Disease)
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Key Therapies for Iron Overload

Efficacy Chart >>
  1. Chelation Therapy (Therapy, Chelation) : 27 outcomes 16 studies in 292 results
  2. Blood Transfusion (Blood Transfusions) : 4 outcomes 8 studies in 231 results
  3. Renal Dialysis (Hemodialysis) : 4 outcomes 6 studies in 74 results
  4. Transplantation (Transplant Recipients) : 3 outcomes 6 studies in 53 results
  5. Erythrocyte Transfusion : 2 outcomes 1 study in 51 results
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