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Inclusion Body Myositis Summary

Description: Progressive myopathies characterized by the presence of inclusion bodies on muscle biopsy. Sporadic and hereditary forms have been described. The sporadic form is an acquired, adult-onset inflammatory vacuolar myopathy affecting proximal and distal muscles. Familial forms usually begin in childhood and lack inflammatory changes. Both forms feature intracytoplasmic and intranuclear inclusions in muscle tissue. (Adams et al., Principles of Neurology, 6th ed, pp1409-10)

Also Known As: Myositis, Inclusion Body; Inclusion Body Myopathy, Sporadic; Inclusion Body Myositis, Sporadic; Myositis, Inclusion Body, Sporadic; Sporadic Inclusion Body Myositis Show All >>

Networked: 476 relevant articles (17 outcomes, 55 trials/studies) for this Disease

Key Drugs and Agents for Inclusion Body Myositis

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Intravenous Immunoglobulins (IVIG) : 8 outcomes 13 studies in 27 results : FDA 1
  2. Immunoglobulins (Immunoglobulin) : 2 outcomes 10 studies in 21 results : IBA
  3. Immunoglobulin M (IgM) : 2 outcomes 2 studies in 5 results : IBA
  4. Adrenal Cortex Hormones (Corticosteroids) : 2 outcomes in 11 results : IBA
  5. Myelin-Associated Glycoprotein (S-MAG) : 1 outcome 2 studies in 3 results : IBA
  6. Monoclonal Antibodies : 1 outcome 1 study in 6 results : IBA
  7. Steroids : 1 outcome 1 study in 4 results : IBA
  8. alemtuzumab (Campath) : 1 outcome 1 study in 3 results : FDA 2
  9. Immunosuppressive Agents (Immunosuppressants) : 1 outcome 1 study in 2 results : IBA
  10. Amyloid (Amyloid Fibrils) : 1 outcome in 78 results : IBA
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Diseases Related to Inclusion Body Myositis

  1. Dermatomyositis (Dermatopolymyositis)
  2. Polymyositis
  3. Myositis (Idiopathic Inflammatory Myopathies)
  4. Polyneuropathies (Polyneuropathy)
  5. Inflammation
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Key Therapies for Inclusion Body Myositis

Efficacy Chart >>
  1. Resistance Training : 2 outcomes 1 study in 3 results
  2. Mesenchymal Stem Cell Transplantation : 1 outcome in 1 result
  3. Tendon Transfer : 1 outcome in 1 result
  4. Activities of Daily Living (ADL) : 1 outcome in 1 result
  5. Denervation : 1 study in 7 results
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