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Ischemic Optic Neuropathy (Anterior Ischemic Optic Neuropathy) Summary

Description: Ischemic injury to the OPTIC NERVE which usually affects the OPTIC DISK (optic neuropathy, anterior ischemic) and less frequently the retrobulbar portion of the nerve (optic neuropathy, posterior ischemic). The injury results from occlusion of arterial blood supply which may result from TEMPORAL ARTERITIS; ATHEROSCLEROSIS; COLLAGEN DISEASES; EMBOLISM; DIABETES MELLITUS; and other conditions. The disease primarily occurs in the sixth decade or later and presents with the sudden onset of painless and usually severe monocular visual loss. Anterior ischemic optic neuropathy also features optic disk edema with microhemorrhages. The optic disk appears normal in posterior ischemic optic neuropathy. (Glaser, Neuro-Ophthalmology, 2nd ed, p135)

Also Known As: Anterior Ischemic Optic Neuropathy; Posterior Ischemic Optic Neuropathy; Optic Neuropathy, Ischemic; Optic Neuropathy, Anterior Ischemic; Optic Neuropathy, Posterior Ischemic Show All >>

Networked: 507 relevant articles (20 outcomes, 59 trials/studies) for this Disease

Key Drugs and Agents for Ischemic Optic Neuropathy

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Adrenal Cortex Hormones (Corticosteroids) : 3 outcomes in 14 results : IBA
  2. Steroids : 2 outcomes 1 study in 8 results : IBA
  3. Oxygen : 1 outcome 2 studies in 6 results : IBA
  4. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor) : 1 outcome 1 study in 6 results : IBA
  5. ranibizumab (Lucentis) : 1 outcome 1 study in 4 results : FDA 2
  6. Granulocyte Colony-Stimulating Factor (G-CSF) : 1 outcome 1 study in 2 results : IBA
  7. Arginine (L-Arginine) : 1 outcome 1 study in 1 result : FDA 19
  8. Methylprednisolone : 1 outcome in 2 results : FDA 18 Generic
  9. Alprostadil (Muse) : 1 outcome in 2 results : FDA 8 Generic
  10. Endothelial Growth Factors : 1 outcome in 1 result : IBA
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Diseases Related to Ischemic Optic Neuropathy

  1. Optic Nerve Diseases (Optic Neuropathy)
  2. Giant Cell Arteritis (Horton Disease)
  3. Retinal Artery Occlusion
  4. Ischemic Optic Neuropathy (Anterior Ischemic Optic Neuropathy)
  5. Glaucoma
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Key Therapies for Ischemic Optic Neuropathy

Efficacy Chart >>
  1. Decompression : 7 outcomes 22 studies in 38 results
  2. Hemodilution : 1 outcome 1 study in 4 results
  3. Intravitreal Injections : 1 outcome in 7 results
  4. Hyperbaric Oxygenation : 1 outcome in 3 results
  5. Blood Component Removal (Apheresis) : 1 outcome in 3 results
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