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Proliferating Cell Nuclear Antigen (PCNA) Summary

Description: Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading and lagging strands at the replication fork during DNA replication. PCNA expression correlates with the proliferation activity of several malignant and non-malignant cell types.

Also Known As: PCNA; Antigen, Proliferating Cell Nuclear

Networked: 4700 relevant articles (114 outcomes, 648 trials/studies) for this Bio-Agent

Key Diseases for which Proliferating Cell Nuclear Antigen is Relevant

  1. Neoplasms (Cancer) : 48 outcomes 154 studies in 1853 results
  2. Carcinoma (Carcinomatosis) : 7 outcomes 60 studies in 477 results
  3. Neoplasm Metastasis (Metastasis) : 7 outcomes 27 studies in 226 results
  4. Inflammation : 4 outcomes 9 studies in 81 results
  5. Squamous Cell Carcinoma (Epidermoid Carcinoma) : 3 outcomes 30 studies in 189 results
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Drugs Related to Proliferating Cell Nuclear Antigen

  1. Proliferating Cell Nuclear Antigen (PCNA)
  2. Biological Markers (Surrogate Marker)
  3. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
  4. Phosphotransferases (Kinase)
  5. DNA (Deoxyribonucleic Acid)
  6. Antigens
  7. Proteins (Proteins, Gene)
  8. Cyclins
  9. Caspase 3 (Caspase-3)
  10. Transferases
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Therapies Related to Proliferating Cell Nuclear Antigen

  1. Heterologous Transplantation (Xenotransplantation)
  2. Drug Therapy (Chemotherapy)
  3. Lasers (Laser)
  4. Transplantation (Transplant Recipients)
  5. Photochemotherapy (Photodynamic Therapy)
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