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Interleukin-12 (IL 12) Summary

Description: A heterodimeric cytokine that plays a role in innate and adaptive immune responses. Interleukin-12 is a 70 kDa protein that is composed of covalently linked 40 kDa and 35 kDa subunits. It is produced by DENDRITIC CELLS; MACROPHAGES and a variety of other immune cells and plays a role in the stimulation of INTERFERON-GAMMA production by T-LYMPHOCYTES and NATURAL KILLER CELLS.

Also Known As: IL 12; Interleukin 12; IL12; Interleukin-12 p70; Cytotoxic Lymphocyte Maturation Factor Show All >>

Networked: 6553 relevant articles (534 outcomes, 884 trials/studies) for this Bio-Agent

Key Diseases for which Interleukin-12 is Relevant

  1. Neoplasms (Cancer) : 187 outcomes 232 studies in 1529 results
  2. Infection : 94 outcomes 102 studies in 1547 results
  3. Psoriasis (Pustulosis Palmaris et Plantaris) : 32 outcomes 29 studies in 182 results
  4. Neoplasm Metastasis (Metastasis) : 28 outcomes 22 studies in 161 results
  5. Melanoma (Melanoma, Malignant) : 15 outcomes 32 studies in 155 results
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Drugs Related to Interleukin-12

  1. Cytokines
  2. Interleukin-12 (IL 12)
  3. Interleukin-2 (IL2)
  4. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
  5. Interleukin-10 (Interleukin 10)
  6. Interleukins
  7. adjuvant P40 (P 40)
  8. Interferon-gamma (Interferon, gamma)
  9. Interleukin-23 (Interleukin 23)
  10. DNA (Deoxyribonucleic Acid)
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Therapies Related to Interleukin-12

  1. Immunotherapy
  2. Heterologous Transplantation (Xenotransplantation)
  3. Injections
  4. Oral Administration
  5. Drug Therapy (Chemotherapy)
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