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ATP-Binding Cassette Transporters (ABC Transporters) Summary

Description: A family of MEMBRANE TRANSPORT PROTEINS that require ATP hydrolysis for the transport of substrates across membranes. The protein family derives its name from the ATP-binding domain found on the protein.

Also Known As: ABC Transporters; ATP Binding Cassette Transporters; Transporters, ABC; Transporters, ATP-Binding Cassette

Networked: 676 relevant articles (15 outcomes, 63 trials/studies) for this Bio-Agent

Key Diseases for which ATP-Binding Cassette Transporters is Relevant

  1. Neoplasms (Cancer) : 3 outcomes 17 studies in 275 results
  2. Alzheimer Disease (Alzheimer's Disease) : 2 outcomes in 9 results
  3. Breast Neoplasms (Breast Cancer) : 1 outcome 11 studies in 140 results
  4. Carcinoma (Carcinomatosis) : 1 outcome 4 studies in 10 results
  5. Adenocarcinoma : 1 outcome 4 studies in 5 results
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Drugs Related to ATP-Binding Cassette Transporters

  1. P-Glycoprotein
  2. Adenosine Triphosphate (ATP)
  3. Enzymes
  4. Proteins (Proteins, Gene)
  5. Scavenger Receptors (Scavenger Receptor)
  6. Paclitaxel (Taxol)
  7. Peptides
  8. Curcumin
  9. Apolipoprotein A-I (Apolipoprotein A1)
  10. NF-kappa B (NF-kB)
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Therapies Related to ATP-Binding Cassette Transporters

  1. Drug Therapy (Chemotherapy)
  2. Chinese Traditional Medicine (Traditional Chinese Medicine)
  3. Heterologous Transplantation (Xenotransplantation)
  4. Therapeutics

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