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Olfactory Esthesioneuroblastoma (Esthesioneuroblastoma) Summary

Description: A malignant olfactory neuroblastoma arising from the olfactory epithelium of the superior nasal cavity and cribriform plate. It is uncommon (3% of nasal tumors) and rarely is associated with the production of excess hormones (e.g., SIADH, Cushing Syndrome). It has a high propensity for multiple local recurrences and bony metastases. (From Holland et al., Cancer Medicine, 3rd ed, p1245; J Laryngol Otol 1998 Jul;112(7):628-33)

Also Known As: Esthesioneuroblastoma; Esthesioneuroblastoma, Olfactory; Esthesioneuroblastoma, Paranasal Sinus-Nasal Cavity; Aesthesioneuroblastomas; Esthesioneuroblastoma, Paranasal Sinus Nasal Cavity Show All >>

Networked: 258 relevant articles (12 outcomes, 18 trials/studies) for this Disease

Key Drugs and Agents for Olfactory Esthesioneuroblastoma

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Protons (Proton) : 2 outcomes in 6 results : IBA
  2. Nasopharyngeal carcinoma : 1 outcome 1 study in 11 results : IBA
  3. Cisplatin (Platino) : 1 outcome 1 study in 4 results : FDA 6 Generic
  4. Etoposide (VP 16) : 1 outcome 1 study in 3 results : FDA 16 Generic
  5. Ifosfamide : 1 outcome 1 study in 2 results : FDA 7 Generic
  6. Monoclonal Antibodies : 1 outcome in 3 results : IBA
  7. anti-synaptophysin : 1 outcome in 1 result : IBA
  8. S100 Proteins (S 100 Protein) : 3 studies in 5 results : IBA
  9. Hormones : 2 studies in 12 results : IBA
  10. Peroxidase (Myeloperoxidase) : 1 study in 3 results : IBA
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Diseases Related to Olfactory Esthesioneuroblastoma

  1. Melanoma (Melanoma, Malignant)
  2. Neoplasms (Cancer)
  3. Lymphoma (Lymphomas)
  4. Neoplasm Metastasis (Metastasis)
  5. Glioma (Gliomas)
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Key Therapies for Olfactory Esthesioneuroblastoma

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 6 outcomes 3 studies in 48 results
  2. Radiotherapy : 3 outcomes 1 study in 57 results
  3. Combined Modality Therapy : 2 outcomes in 5 results
  4. Craniotomy : 1 outcome in 5 results
  5. Salvage Therapy : 2 studies in 3 results
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