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Primitive Neuroectodermal Tumors (PNET) Summary

728 relevant articles (26 outcomes, 95 trials/studies) found for this Disease

Description: A group of malignant tumors of the nervous system that feature primitive cells with elements of neuronal and/or glial differentiation. Use of this term is limited by some authors to central nervous system tumors and others include neoplasms of similar origin which arise extracranially (i.e., NEUROECTODERMAL TUMORS, PRIMITIVE, PERIPHERAL). This term is also occasionally used as a synonym for MEDULLOBLASTOMA. In general, these tumors arise in the first decade of life and tend to be highly malignant. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2059)

Also Known As: PNET; Primitive Neuroectodermal Tumor; Ependymoblastoma; Tumor, Primitive Neuroectodermal; Spongioblastoma Show All >>

Key Drugs and Agents for Primitive Neuroectodermal Tumors

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Drugs and Important Biological Agents (IBA) related to treatments:
  1. Etoposide (VP 16) : 5 outcomes 1 study in 23 results : FDA 16 Generic
  2. Carboplatin (JM8) : 4 outcomes 1 study in 15 results : FDA 23 Generic
  3. Cyclophosphamide (Cytoxan) : 3 outcomes 4 studies in 15 results : FDA 10
  4. Vincristine (Oncovin) : 3 outcomes 2 studies in 15 results : FDA 18 Generic
  5. Ifosfamide : 2 outcomes 1 study in 12 results : FDA 6 Generic
  6. DNA (Deoxyribonucleic Acid) : 1 outcome 3 studies in 34 results : IBA
  7. Messenger RNA (mRNA) : 1 outcome 3 studies in 32 results : IBA
  8. Antibodies : 1 outcome 3 studies in 25 results : IBA
  9. Keratins (Keratin) : 1 outcome 3 studies in 13 results : IBA
  10. Doxorubicin (Adriamycin) : 1 outcome 1 study in 11 results : FDA 12 Generic
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Diseases Related to Primitive Neuroectodermal Tumors

  1. Primitive Neuroectodermal Tumors (PNET)
  2. Medulloblastoma
  3. Neoplasms (Cancer)
  4. Ewing's Sarcoma (Sarcoma, Ewing)
  5. Brain Neoplasms (Brain Tumor)
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Key Therapies for Primitive Neuroectodermal Tumors

Efficacy Chart >>
  1. Drug Therapy (Chemotherapy) : 8 outcomes 17 studies in 122 results
  2. Adjuvant Chemotherapy : 2 outcomes 4 studies in 14 results
  3. Combination Drug Therapy (Combination Chemotherapy) : 1 outcome 1 study in 4 results
  4. Pancreatectomy : 1 outcome 1 study in 3 results
  5. Heterologous Transplantation (Xenotransplantation) : 4 studies in 11 results
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