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Exfoliation Syndrome Summary

Description: The deposition of flaky, translucent fibrillar material most conspicuous on the anterior lens capsule and pupillary margin but also in both surfaces of the iris, the zonules, trabecular meshwork, ciliary body, corneal endothelium, and orbital blood vessels. It sometimes forms a membrane on the anterior iris surface. Exfoliation refers to the shedding of pigment by the iris. (Newell, Ophthalmology, 7th ed, p380)

Also Known As: Exfoliative Syndrome; Pseudo-Exfoliation Syndrome; Exfoliation Syndromes; Exfoliative Syndromes; Pseudo Exfoliation Syndrome Show All >>

Networked: 311 relevant articles (11 outcomes, 40 trials/studies) for this Disease

Key Drugs and Agents for Exfoliation Syndrome

Efficacy Chart >>
Drugs and Important Biological Agents (IBA) related to treatments:
  1. Timolol (Blocadren) : 2 outcomes in 4 results : FDA 56 Generic
  2. bimatoprost (Lumigan) : 2 outcomes in 4 results : FDA 3
  3. Argon : 1 outcome in 5 results : IBA
  4. latanoprost (Xalatan) : 1 outcome in 3 results : FDA 3
  5. ibopamine : 1 outcome in 1 result : IBA
  6. Protein-Lysine 6-Oxidase (Lysyl Oxidase) : 7 studies in 33 results : IBA
  7. Retinaldehyde (Retinal) : 2 studies in 11 results : IBA
  8. Homocysteine : 2 studies in 10 results : IBA
  9. Clusterin : 2 studies in 5 results : IBA
  10. Matrix Metalloproteinases : 2 studies in 5 results : IBA
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Diseases Related to Exfoliation Syndrome

  1. Glaucoma
  2. Cataract (Cataracts)
  3. Open-Angle Glaucoma (Glaucoma, Open Angle)
  4. Dislocations
  5. Angle-Closure Glaucoma (Glaucoma, Angle Closure)
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Key Therapies for Exfoliation Syndrome

Efficacy Chart >>
  1. Trabeculectomy (Trabeculoplasty) : 4 outcomes in 15 results
  2. Phacoemulsification : 3 outcomes 4 studies in 42 results
  3. Lasers (Laser) : 3 outcomes 2 studies in 23 results
  4. Intraocular Lenses (Intraocular Lens) : 3 studies in 32 results
  5. Cataract Extraction : 3 studies in 27 results
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